Acute human immunodeficiency virus type 1 (HIV-1) infection is a transient symptomatic
illness associated with high-titer HIV-1 replication and a robust and expansive immunologic …

Measures to prevent sexual mucosal transmission of human immunodeficiency virus (HIV)-1
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …

BACKGROUND Understanding HIV dynamics across the human body is important for cure
efforts. This goal has been hampered by technical difficulties and the challenge of obtaining …

HIV-1 is transmitted by sexual contact across mucosal surfaces, by maternal-infant
exposure, and by percutaneous inoculation. For reasons that are still incompletely …

Transmission through sexual contact accounts for 75 to 85 percent of the nearly 28 million
infections with the human immunodeficiency virus (HIV) that have occurred so far. 1 The …

HIV-1 infection typically results from the transmission of a single viral variant, the
transmitted/founder (T/F) virus. Studies of these HIV-1 variants provide critical information …

For more than two decades, HIV has infected millions of people worldwide each year
through mucosal transmission. Our knowledge of how HIV secures a foothold at both the …

Background Transmission of HIV-1 is predominantly by heterosexual contact in sub-
Saharan Africa, where sexually transmitted diseases (STDs) are also common …

Accurate identification of the transmitted virus and sequences evolving from it could be
instrumental in elucidating the transmission of human immunodeficiency virus type 1 (HIV-1) …

Heterosexual transmission accounts for the majority of human immunodeficiency virus–1
(HIV-1) infections worldwide, yet the viral properties that determine transmission fitness or …