Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

N Sallam, I Laher - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Creatine‐kinase‐and exercise‐related muscle damage implications for muscle performance and recovery

MF Baird, SM Graham, JS Baker… - Journal of nutrition and …, 2012 - Wiley Online Library
The appearance of creatine kinase (CK) in blood has been generally considered to be an
indirect marker of muscle damage, particularly for diagnosis of medical conditions such as …

Employee retirement: A review and recommendations for future investigation

M Wang, KS Shultz - Journal of Management, 2010 - journals.sagepub.com
Despite the obvious importance of retirement to employees, their employing organizations,
and the larger society, the last comprehensive review of employee retirement in the field of …

Retirement adjustment: A review of theoretical and empirical advancements.

M Wang, K Henkens, H Van Solinge - American psychologist, 2011 - psycnet.apa.org
In this article, we review both theoretical and empirical advancements in retirement
adjustment research. After reviewing and integrating current theories about retirement …

Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

DR Seals, JN Justice, TJ LaRocca - The Journal of physiology, 2016 - Wiley Online Library
Most nations of the world are undergoing rapid and dramatic population ageing, which
presents great socio‐economic challenges, as well as opportunities, for individuals, families …

Profiling retirees in the retirement transition and adjustment process: examining the longitudinal change patterns of retirees' psychological well-being.

M Wang - Journal of applied psychology, 2007 - psycnet.apa.org
The author used role theory, continuity theory, and the life course perspective to form
hypotheses regarding the different retirement transition and adjustment patterns and how …

Reactive oxygen species in skeletal muscle signaling

E Barbieri, P Sestili - Journal of signal transduction, 2012 - Wiley Online Library
Generation of reactive oxygen species (ROS) is a ubiquitous phenomenon in eukaryotic
cells′ life. Up to the 1990s of the past century, ROS have been solely considered as toxic …

The mitochondrial energy transduction system and the aging process

A Navarro, A Boveris - American Journal of Physiology-Cell …, 2007 - journals.physiology.org
Aged mammalian tissues show a decreased capacity to produce ATP by oxidative
phosphorylation due to dysfunctional mitochondria. The mitochondrial content of rat brain …

Redox control of skeletal muscle regeneration

E Le Moal, V Pialoux, G Juban… - Antioxidants & redox …, 2017 - liebertpub.com
Skeletal muscle shows high plasticity in response to external demand. Moreover, adult
skeletal muscle is capable of complete regeneration after injury, due to the properties of …