Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …

Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …

The guanylate binding protein (GBP) family of interferon‐inducible GTP ases promotes
antimicrobial immunity and cell death. During bacterial infection, multiple mouse Gbps …

With advances in artificial intelligence (AI) technologies, the development and
implementation of digital food systems are becoming increasingly possible. There is …

Innate immune pattern recognition receptors, such as the Toll-like receptors (TLRs), are key
mediators of the immune response to infection and central to our understanding of health …

The intracellular parasite Toxoplasma gondii has long provided a tractable experimental
system to investigate how the immune system deals with intracellular infections. This review …

In the era of antimicrobial resistance, the prevalence of multidrug-resistant microorganisms
that resist conventional antibiotic treatment has steadily increased. Thus, it is now …

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

Apicomplexan parasites, such as Toxoplasma gondii, have specific adaptations that enable
invasion and exit from the host cell. Owing to the phylogenetic distance between …

Disruption of cellular activities by pathogen virulence factors can trigger innate immune
responses. Interferon-γ (IFN-γ)–inducible antimicrobial factors, such as the guanylate …