The emerging functions and mechanisms of mammalian fatty acid–binding proteins
Fatty acid–binding proteins (FABPs) are abundant intracellular proteins that bind long-chain
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …
The role of dynamics in modulating ligand exchange in intracellular lipid binding proteins
Lipids are essential for many biological processes and crucial in the pathogenesis of several
diseases. Intracellular lipid-binding proteins (iLBPs) provide mobile hydrophobic binding …
diseases. Intracellular lipid-binding proteins (iLBPs) provide mobile hydrophobic binding …
[HTML][HTML] Quantitative assessment of liver steatosis and affected pathways with molecular imaging and proteomic profiling
Current assessment of non-alcoholic fatty liver disease (NAFLD) with histology is time-
consuming, insensitive to early-stage detection, qualitative, and lacks information on …
consuming, insensitive to early-stage detection, qualitative, and lacks information on …
Deconstructing honeybee vitellogenin: novel 40 kDa fragment assigned to its N terminus
H Havukainen, Ø Halskau… - Journal of …, 2011 - journals.biologists.com
Vitellogenin, an egg-yolk protein precursor common to oviparous animals, is found
abundantly in honeybee workers–a caste of helpers that do not usually lay eggs. Instead …
abundantly in honeybee workers–a caste of helpers that do not usually lay eggs. Instead …
[HTML][HTML] Interaction of Hsp90 with phospholipid model membranes
M Zhang, D Wang, P Li, C Sun, R Xu, Z Geng… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract Heat shock protein 90 (Hsp90) is an essential molecular chaperone with versatile
functions in cell homeostatic control under both normal and stress conditions. Hsp90 has …
functions in cell homeostatic control under both normal and stress conditions. Hsp90 has …
[HTML][HTML] Protein-membrane interaction and fatty acid transfer from intestinal fatty acid-binding protein to membranes: support for a multistep process
LJ Falomir-Lockhart, L Laborde, PC Kahn… - Journal of Biological …, 2006 - ASBMB
Fatty acid transfer from intestinal fatty acid-binding protein (IFABP) to phospholipid
membranes occurs during protein-membrane collisions. Electrostatic interactions involving …
membranes occurs during protein-membrane collisions. Electrostatic interactions involving …
Interaction of enterocyte FABPs with phospholipid membranes: clues for specific physiological roles
Intestinal and liver fatty acid binding proteins (IFABP and LFABP, respectively) are cytosolic
soluble proteins with the capacity to bind and transport hydrophobic ligands between …
soluble proteins with the capacity to bind and transport hydrophobic ligands between …
[HTML][HTML] Conformational exchange of fatty acid binding protein induced by protein-nanodisc interactions
Fatty acid binding proteins (FABPs) can facilitate the transfer of long-chain fatty acids
between intracellular membranes across considerable distances. The transfer process …
between intracellular membranes across considerable distances. The transfer process …
[HTML][HTML] Similar structures but different mechanisms: Prediction of FABPs–membrane interaction by electrostatic calculation
The role of fatty acid binding proteins as intracellular fatty acid transporters may require their
direct interaction with membranes. In this way different mechanisms have been previously …
direct interaction with membranes. In this way different mechanisms have been previously …
[HTML][HTML] Probing the interaction of brain fatty acid binding protein (B-FABP) with model membranes
Brain fatty acid-binding protein (B-FABP) interacts with biological membranes and delivers
polyunsaturated fatty acids (FAs) via a collisional mechanism. The binding of FAs in the …
polyunsaturated fatty acids (FAs) via a collisional mechanism. The binding of FAs in the …