Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

Franz diffusion cell and its implication in skin permeation studies

M Kumar, A Sharma, S Mahmood… - Journal of Dispersion …, 2024 - Taylor & Francis
Franz diffusion cell was primarily used to evaluate the permeability and stability of
formulations such as topical (gels and creams) and transdermal (lipid nanoparticle …

[HTML][HTML] Evaluation of formulation parameters on permeation of ibuprofen from topical formulations using Strat-M® membrane

PK Bolla, BA Clark, A Juluri, HS Cheruvu, J Renukuntla - Pharmaceutics, 2020 - mdpi.com
Topical drug delivery is an attractive alternative to conventional methods because of
advantages such as non-invasive delivery, by-pass of first pass metabolism, and improved …

Transdermal drug delivery system through polymeric microneedle: A recent update

M Azmana, S Mahmood, AR Hilles, UK Mandal… - Journal of Drug Delivery …, 2020 - Elsevier
As non-toxic, biodegradable, biocompatible materials, the polymeric microneedles have a
great significance in terms of delivering therapeutic drug molecules through the skin. They …

Gel formulations for topical treatment of skin cancer: a review

M Slavkova, B Tzankov, T Popova, C Voycheva - Gels, 2023 - mdpi.com
Skin cancer, with all its variations, is the most common type of cancer worldwide.
Chemotherapy by topical application is an attractive strategy because of the ease of …

[HTML][HTML] Skin interaction, permeation, and toxicity of silica nanoparticles: Challenges and recent therapeutic and cosmetic advances

RP Morais, S Hochheim, CC de Oliveira… - International Journal of …, 2022 - Elsevier
Silica nanoparticles (SNPs) received more attention with the emergence of nanotechnology
with the aim and promise of becoming innovative drug delivery systems. They have been …

Polymeric microneedles for transdermal drug delivery-a review of recent studies

Z Karim, P Karwa, SRR Hiremath - Journal of Drug Delivery Science and …, 2022 - Elsevier
Transdermal drug delivery is contemplated as one of the top appealing routes for
pharmaceutically active ingredients administration owing to the several benefits, specifically …

Development, characterization and use of liposomes as amphipathic transporters of bioactive compounds for melanoma treatment and reduction of skin inflammation …

ED Castañeda-Reyes, MJ Perea-Flores… - International journal …, 2020 - Taylor & Francis
The skin is the largest organ in the human body, providing a barrier to the external
environment. It is composed of three layers: epidermis, dermis and hypodermis. The most …