As many diseases have been shown to have several or indirect causes (ie are multifactorial)
the question is what is the relative importance of each factor in a given disease? Also, what …

Overweight and obesity have been suggested to be associated with periodontitis as
published in studies and narrative summaries. This project presents results of a systematic …

Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

Aging is a biological process characterized by time-dependent functional declines that are
influenced by changes in redox status and by oxidative stress-induced inflammatory …

Background: The emergence of periodontal medicine has increased interest in defining the
serologic profiles of inflammatory mediators in subjects with periodontitis. Thus, the aim of …

Background Periodontitis, the most prevalent chronic inflammatory disease, has been
related to cardiovascular diseases. Autophagy provides a mechanism for the turnover of …

Background Recent studies have suggested that periodontal disease increases the risk of
atherothrombotic disease. Atherosclerosis has been characterized as a chronic …

Oxidative stress is one of the factors that could explain the pathophysiological mechanism of
inflammatory conditions that occur in cardiovascular disease (CVD) and periodontitis. Such …

Macroautophagy/autophagy is a conserved lysosomal degradation process essential for cell
physiology and human health. By regulating apoptosis, inflammation, pathogen clearance …

Periodontitis is a chronic inflammatory disease characterized by destruction of periodontal
tissue ultimately leading to bone destruction and has been associated with other …