The use of computational fluid dynamics in the development of ventricular assist devices

KH Fraser, ME Taskin, BP Griffith, ZJ Wu - Medical engineering & physics, 2011 - Elsevier
Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …

Analysis of rotary ventricular assist devices using CFD technique—a review

PK Shukla, R Mishra, RP Tewari - Proceedings of the …, 2023 - journals.sagepub.com
With the increasing focus on reducing deaths because of heart ailments, considerable
emphasis has been directed toward the development of ventricular assist devices (VADs) …

Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: glycoprotein Ibα and glycoprotein VI

Z Chen, NK Mondal, J Ding, J Gao, BP Griffith… - Thrombosis research, 2015 - Elsevier
Introduction The structural integrity of platelet receptors is essential for platelets to function
normally in hemostasis and thrombosis in response to physiological and pathological …

Haemolysis in patients with ventricular assist devices: major differences between systems

C Heilmann, U Geisen, C Benk… - European journal of …, 2009 - academic.oup.com
Introduction: Implantation of a ventricular assist device (VAD) is a seminal therapeutic option
for patients with terminal cardiac failure. However, haemolysis remains a clinically relevant …

Optimisation of the Sputnik-VAD design

SV Selishchev, DV Telyshev - The International journal of …, 2016 - journals.sagepub.com
Purpose Miniaturisation of VADs can offer important benefits, including less invasive
implantation techniques and more versatility in patient selection. The aim of this work was to …

The progress in the novel pediatric rotary blood pump Sputnik development

D Telyshev, M Denisov, A Pugovkin… - Artificial …, 2018 - Wiley Online Library
In this work, the study results of an implantable pediatric rotary blood pump (PRBP) are
presented. They show the results of the numerical simulation of fluid flow rates in the pump …

Numerical assessment of hemodynamic perspectives of a left ventricular assist device and subsequent proposal for improvisation

PK Ray, AK Das, PK Das - Computers in Biology and Medicine, 2022 - Elsevier
Due to the unavailability of donors, the use of left ventricular assist devices has emerged to
be a reliable line of alternative treatment for heart failure. However, ventricular assist devices …

Channel impeller design for centrifugal blood pump in hybrid pediatric total artificial heart: Modeling, magnet integration, and hydraulic experiments

M Hirschhorn, N Catucci, SW Day, RM Stevens… - Artificial …, 2023 - Wiley Online Library
Background The purpose of this research is to address ongoing device shortfalls for
pediatric patients by developing a novel pediatric hybrid total artificial heart (TAH). The …

Stochastic simulation of the FDA centrifugal blood pump benchmark

MS Karimi, P Razzaghi, M Raisee, P Hendrick… - … and Modeling in …, 2021 - Springer
In the present study, the effect of physical and operational uncertainties on the
hydrodynamic and hemocompatibility characteristics of a centrifugal blood pump designed …

Computational design and experimental testing of a novel axial flow LVAD

A Untaroiu, HG Wood, PE Allaire, AL Throckmorton… - ASAIO …, 2005 - journals.lww.com
Thousands of cardiac failure patients per year in the United States could benefit from long-
term mechanical circulatory support as destination therapy. To provide an improvement over …