Cisplatin (cDDP) is an anticancer agent that is widely used in the treatment of many solid
tumors. A major obstacle to successful cDDP-based chemotherapy, however, is the intrinsic …

Over the past decades, promising therapies targeting different signaling pathways have
emerged. Among these pathways, apoptosis has been well investigated and targeted to …

Combination of chemotherapy and gene therapy provides an effective strategy for cancer
treatment. However, the lack of suitable codelivery systems with efficient endo/lysosomal …

The role of autophagy in cisplatin anticancer action was investigated using human U251
glioma, rat C6 glioma and mouse L929 fibrosarcoma cell lines. A dose‐and time‐dependent …

Aqueous extract of Trametes robiniophila murr (Huaier) has been commonly used in China
for cancer complementary therapy in recent years; however, the mechanisms of its …

Theranostics of platinum (Pt)-based chemotherapy are able to self-track the biodistribution
and pharmacokinetics while performing therapeutic effects. Pt-based CT imaging is …

Cisplatin-based therapy is one of the most important chemotherapy treatments for cancers.
However, its efficacy is greatly limited by drug resistance and undesirable side effects …

Metastatic disease is the most common mechanism of death in patients with advanced
bladder cancer. As for most solid tumors, chemotherapy remains the only realistic option for …

A multivalent phosphorus dendrimer 1G 3 and its corresponding Cu-complex, 1G 3-Cu have
been recently identified as agents retaining high antiproliferative potency. This …

Purpose The mechanism of resistance to cisplatin during treatment of bladder cancer (BC)
has been a subject of intense investigation in clinical research. This study aims to identify …