Cancer is one of the most significant health challenges worldwide. Various techniques, tools
and therapeutics/materials have been developed in the last few decades for the treatment of …

Acetylcholinesterase (AChE) is a critical target in the prevention of Alzheimer's Disease (AD)
progression. With the goal of developing potential acetylcholinesterase inhibitors, a new …

Cancer is a progressive disease that is frequently encountered worldwide. The incidence of
cancer is increasing with the changing living conditions around the world. The side-effect …

Bile acids (BAs) constitute essential components of cholesterol metabolites that are
synthesized in the liver, stored in the gallbladder, and excreted into the intestine through the …

Chlamydia trachomatis and human papilloma virus (HPV) are the two most common
sexually transmitted infections among women. HPV infection can increase the risk of cervical …

Thirteen diarylurea derivatives were designed and synthesized as sorafenib mimetics. The
cytotoxic activity of the newly synthesized entities towards human breast cancer cell …

The synthesis, characterization, and antibacterial and antioxidant activity of thiadiazole-
deoxycholic/lithocholic acid conjugates are described in this communication. The structures …

Bacterial sepsis is a mortal syndromic disease characterized by a complex pathophysiology
that hinders effective targeted therapy. This study aimed to develop multifunctional …

Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by
glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as …

Novel series of nitric oxide-releasing thiazolidine-2, 4-diones (NO-TZD-3a-d, 5, 6) and 3, 4, 5-
trimethoxychalcone-based multifunctional 1, 4-dihydropyrimidines (CDHPM-10a-g) have …