Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …

Introduction: Historically, the global community has focused on the control of symptomatic
malaria. However, interest in asymptomatic malaria has been growing, particularly in the …

Panax notoginseng (PN) is a Chinese medicinal herb that is traditionally used to treat
inflammation and immune-related diseases. Its major active constituents are saponins, the …

Individuals growing up in malaria endemic areas gradually develop protection against
clinical malaria and passive transfer experiments in humans have demonstrated that this …

Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids
and play an important role on host defense. It has been demonstrated that upon infection or …

Malaria parasite infection weakens colonization resistance against Salmonella enterica
serovar (S.) Typhimurium. S. Typhimurium is a member of the Enterobacterales, a taxon that …

Salmonella can be categorized into many serotypes, which are specific to known hosts or
broadhosts. It makes no difference which one of the serotypes would penetrate the …

Globally, malaria continues to be an enormous public health burden, with concomitant
parasite-induced damage to the gastrointestinal (GI) barrier resulting in bacteremia …

An increase in mast cells (MCs) and MCs mediators has been observed in malaria-
associated bacteremia, however, the role of these granulocytes in malarial immunity is …