Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity

M Bosma, S Kersten, MKC Hesselink… - Progress in lipid …, 2012 - Elsevier
Ectopic fat accumulation has been linked to lipotoxic events, including the development of
insulin resistance in skeletal muscle. Indeed, intramyocellular lipid storage is strongly …

Quantitative 1H MRI and MRS of fatty acid composition

P Peterson, L Trinh, S Månsson - Magnetic Resonance in …, 2021 - Wiley Online Library
Adipose tissue as well as other depots of fat (triglycerides) are increasingly being
recognized as active contributors to the human function and metabolism. In addition to the …

Physiological changes and pathological pain associated with sedentary lifestyle-induced body systems fat accumulation and their modulation by physical exercise

E Verdú, J Homs, P Boadas-Vaello - International journal of …, 2021 - mdpi.com
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Marrow fat composition in anorexia nervosa

MA Bredella, PK Fazeli, SM Daley, KK Miller, CJ Rosen… - Bone, 2014 - Elsevier
Purpose Women with anorexia nervosa (AN) have increased marrow fat despite severe
depletion of body fat. Recent studies have suggested that marrow fat composition may serve …

Abnormal peri-organ or intra-organ fat (APIFat) deposition: an underestimated predictor of vascular risk?

N Katsiki, VG Athyros… - Current vascular …, 2016 - ingentaconnect.com
Adipose tissue, a major endocrine organ, consists of brown and white adipocytes. Brown fat
may play a beneficial role in cardiometabolic disorders. Brown adipose tissue can also …

Intramuscular fat in gluteus maximus for different levels of physical activity

MA Belzunce, J Henckel, A Di Laura, A Hart - Scientific reports, 2021 - nature.com
We aimed to determine if gluteus maximus (GMAX) fat infiltration is associated with different
levels of physical activity. Identifying and quantifying differences in the intramuscular fat …

21st century advances in multimodality imaging of obesity for care of the cardiovascular patient

IJ Neeland, T Yokoo, OD Leinhard, CJ Lavie - Cardiovascular Imaging, 2021 - jacc.org
Although obesity is typically defined by body mass index criteria, this does not differentiate
true body fatness, as this includes both body fat and muscle. Therefore, other fat depots may …

Multiomics integrative analysis for discovering the potential mechanism of dioscin against hyperuricemia mice

Y Tan, L Wang, J Gao, J Ma, H Yu… - Journal of Proteome …, 2020 - ACS Publications
Hyperuricemia is a well-known key risk factor for gout and can cause a variety of metabolic
diseases. Several studies have shown that dioscin could improve metabolic symptoms and …

Quantitative analysis concerning atrophy and fat infiltration of the multifidus muscle with magnetic resonance spectroscopy in chronic low back pain

I Ogon, T Takebayashi, H Takashima… - Spine surgery and …, 2019 - jstage.jst.go.jp
Introduction: Magnetic resonance spectroscopy (MRS) enables detailed analysis of the
composition of muscular fat tissues such as intramyocellular lipids (IMCLs) and …

Magnetic resonance spectroscopic analysis of multifidus muscles lipid content and association with spinopelvic malalignment in chronic low back pain

I Ogon, T Takebayashi, H Takashima… - The British Journal of …, 2017 - academic.oup.com
Objective: To analyze intramyocellular lipids (IMCLs) and extramyocellular lipids (EMCLs) of
the multifidus muscle (Mm) using MR spectroscopy in chronic low back pain (CLBP) and …