Glycosylation is a successful strategy to alter the pharmacological properties of small
molecules, and it has emerged as a unique approach to expand the chemical space of …

Radical-mediated transformations have emerged as powerful methods for the synthesis of
rare and unnatural branched, deoxygenated, and isomeric sugars. Here, we describe a …

Background Flavonoid glycosides extracted from roots of Scutellaria baicalensis exhibit
strong pharmaceutical antitumor, antioxidative, anti-inflammatory, and antiviral activities …

Plant family 1 glycosyltransferases (UGTs) represent a formidable tool to produce valuable
natural and novel glycosides. Their regio-and stereo-specific one-step glycosylation …

Leishmaniasis, one of the neglected diseases, ranks second to malaria in the cause of
parasitic mortality and morbidity. The present chemotherapeutic regimen faces the …

A genome mining approach was used to identify a hybrid tubercidin–nucleocidin
biosynthetic gene cluster (BGC) in Streptomyces sp. AVP053U2. Analysis of culture extracts …

Salvia plebeia (Lamiaceae) is a valuable medicinal plant widely distributed across Asia and
Oceania. However, the composition and accumulation patterns of its active ingredients in …

Nucleotide sugar (NS) dehydratases play a central role in the biosynthesis of deoxy and
amino sugars, which are involved in a variety of biological functions in all domains of life …

Kidamycins belong to the pluramycin family of antitumor antibiotics that contain di-C-
glycosylated angucycline. Owing to its interesting biological activity, several synthetic …

Natural products (NPs), biomolecules produced by living organisms, inspire the
pharmaceutical industry and research due to their structural characteristics and the …