[HTML][HTML] Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases

J Bai, Y Zhang, C Tang, Y Hou, X Ai, X Chen… - Biomedicine & …, 2021 - Elsevier
Gallic acid (GA), also known as 3, 4, 5-trihydroxybenzoic acid, is a natural secondary
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Gut microbiota metabolites in NAFLD pathogenesis and therapeutic implications

J Chen, L Vitetta - International journal of molecular sciences, 2020 - mdpi.com
Gut microbiota dysregulation plays a key role in the pathogenesis of nonalcoholic fatty liver
disease (NAFLD) through its metabolites. Therefore, the restoration of the gut microbiota and …

[HTML][HTML] Butyrate, a postbiotic of intestinal bacteria, affects pancreatic cancer and gemcitabine response in in vitro and in vivo models

C Panebianco, A Villani, F Pisati, F Orsenigo… - Biomedicine & …, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer. The characteristic
excessive stromatogenesis accompanying the growth of this tumor is believed to contribute …

Role of vitamin K in intestinal health

Y Lai, H Masatoshi, Y Ma, Y Guo, B Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC) generally characterized by clinical symptoms, including malabsorption, intestinal …

Akkermansia muciniphila and Faecalibacterium prausnitzii in Immune-Related Diseases

RMRA Effendi, M Anshory, H Kalim, RF Dwiyana… - Microorganisms, 2022 - mdpi.com
Probiotics and synbiotics are used to treat chronic illnesses due to their roles in immune
system modulation and anti-inflammatory response. They have been shown to reduce …

NAFLD/MASLD and the gut–liver axis: From pathogenesis to treatment options

NG Vallianou, D Kounatidis, S Psallida… - Metabolites, 2024 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) poses an emerging threat topublic health.
Nonalcoholic steatohepatitis (NASH) is reported to be the most rapidly rising cause of …

Effect of non-nutritive sweeteners on the gut microbiota

A Conz, M Salmona, L Diomede - Nutrients, 2023 - mdpi.com
The human gut microbiota, a complex community of microorganisms living in the digestive
tract, consists of more than 1500 species distributed in more than 50 different phyla, with …

Cathelicidin host defense peptides and inflammatory signaling: Striking a balance

MA Alford, B Baquir, FL Santana, EF Haney… - Frontiers in …, 2020 - frontiersin.org
Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates.
While their antibacterial activity toward bacterial cells was the original focus for research …

A mini review on osteoporosis: from biology to pharmacological management of bone loss

KY Chin, BN Ng, MKI Rostam… - Journal of Clinical …, 2022 - mdpi.com
Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass
and microarchitecture, which compromises bone strength. It is a complex multifactorial …