Epidemiology, screening, and prevention of bladder cancer
Context Bladder cancer (BC) represents a significant health problem due to the potential
morbidity and mortality associated with disease burden, which has remained largely …
morbidity and mortality associated with disease burden, which has remained largely …
Epidemiology of bladder cancer: a systematic review and contemporary update of risk factors in 2018
Context Bladder cancer (BC) is a significant health problem, and understanding the risk
factors for this disease could improve prevention and early detection. Objective To provide a …
factors for this disease could improve prevention and early detection. Objective To provide a …
The role of tobacco smoke in bladder and kidney carcinogenesis: a comparison of exposures and meta-analysis of incidence and mortality risks
Context Tobacco smoke includes a mix of carcinogens implicated in the etiology of bladder
cancer (BC) and renal cell cancer (RCC). Objective We reviewed the impact of tobacco …
cancer (BC) and renal cell cancer (RCC). Objective We reviewed the impact of tobacco …
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
J Kim, KW Mouw, P Polak, LZ Braunstein… - Nature …, 2016 - nature.com
Alterations in DNA repair pathways are common in tumors and can result in characteristic
mutational signatures; however, a specific mutational signature associated with somatic …
mutational signatures; however, a specific mutational signature associated with somatic …
[HTML][HTML] Global trends of bladder cancer incidence and mortality, and their associations with tobacco use and gross domestic product per capita
Background Bladder cancer is a major urological disease, with approximately 550 000 new
cases diagnosed in 2018. Objective We examined gender-specific incidence and mortality …
cases diagnosed in 2018. Objective We examined gender-specific incidence and mortality …
[HTML][HTML] Shining a light on xeroderma pigmentosum
JJ DiGiovanna, KH Kraemer - Journal of investigative dermatology, 2012 - Elsevier
Xeroderma pigmentosum (XP) is a rare, autosomal recessive disorder of DNA repair
characterized by sun sensitivity and UV radiation–induced skin and mucous membrane …
characterized by sun sensitivity and UV radiation–induced skin and mucous membrane …
DNA damage response and repair gene alterations are associated with improved survival in patients with platinum-treated advanced urothelial carcinoma
Purpose: Platinum-based chemotherapy remains the standard treatment for advanced
urothelial carcinoma by inducing DNA damage. We hypothesize that somatic alterations in …
urothelial carcinoma by inducing DNA damage. We hypothesize that somatic alterations in …
Cruciferous vegetables, isothiocyanates, and bladder cancer prevention
Bladder cancer is a significant health burden due to its high prevalence, risk of mortality,
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …
Epidemiology of bladder cancer
Bladder cancer is mainly a disease of aging; its incidence and prevalence increase around
the sixth decade and peak in the seventh to eighth decade of life. It is the ninth most …
the sixth decade and peak in the seventh to eighth decade of life. It is the ninth most …
Cancer susceptibility mutations in patients with urothelial malignancies
MI Carlo, V Ravichandran, P Srinavasan… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Urothelial cancers (UCs) have a substantial hereditary component, but, other
than their association with Lynch syndrome, the contribution of genetic risk factors to UC …
than their association with Lynch syndrome, the contribution of genetic risk factors to UC …