G protein-gated inwardly rectifying potassium channels (Kir3/GirK) are important for
maintaining resting membrane potential, cell excitability and inhibitory neurotransmission …

Although it is evident from the literature that altered GABA B receptor function does affect
behavior, these results often do not correspond well. These differences could be due to the …

Members of the heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptor (GPCR) family play key roles in many physiological functions and are extensively …

G protein–coupled receptors (GPCRs) play critical roles in regulating processes such as
cellular homeostasis, responses to stimuli, and cell signaling. Accordingly, GPCRs have …

Extensive debates continue regarding marijuana (Cannabis spp), the most commonly used
illicit substance in many countries worldwide. There has been an exponential increase of …

The regulator of G protein signaling (RGS) family of proteins serves critical roles in G protein-
coupled receptor (GPCR) and heterotrimeric G protein signal transduction. RGS proteins are …

G protein-gated inwardly rectifying K+ (GIRK/Kir3) channels exert a critical inhibitory
influence on neurons. Neuronal GIRK channels mediate the G protein-dependent …

G protein-coupled receptors (GPCRs) transmit information to the cell interior by transducing
external signals to heterotrimeric G protein subunits, Gα and Gβγ subunits, localized on the …

The G-protein-gated inwardly rectifying potassium (Kir3/GIRK) channel is the effector of
many G-protein-coupled receptors (GPCRs). Its dysfunction has been linked to the …

Regulators of G protein signaling (RGS) proteins modulate the physiologic actions of many
neurotransmitters, hormones, and other signaling molecules. Human RGS proteins …