Brain arterioles are active, multicellular complexes whose diameters oscillate at∼ 0.1 Hz.
We assess the physiological impact and spatiotemporal dynamics of vaso-oscillations in the …

The brain's network of perivascular channels for clearance of excess fluids and waste plays
a critical role in the pathogenesis of several neurodegenerative diseases including cerebral …

Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to
play a key role in brain solute transport and clearance. While various drivers for a pulsatile …

Importance Exposure to repetitive head impacts (RHI) is associated with increased risk for
neurodegeneration. Accumulation of toxic proteins due to impaired brain clearance is …

Spontaneous cerebral vasomotion, characterized by∼ 0.1 Hz rhythmic contractility, is crucial
for brain homeostasis. However, our understanding of vasomotion is limited due to a lack of …

Known physical mechanisms of temperature dependence anomalies of water properties
were used to explain the regularities in temperature dependence (TDs) of dynamic …

Flow of cerebrospinal fluid through perivascular pathways in and around the brain may play
a crucial role in brain metabolite clearance. While the driving forces of such flows remain …

Many neurological diseases are characterized by the accumulation of toxic proteins in the
brain. This accumulation has been associated with improper glymphatic clearance from the …

Abstract The Global Burden of Disease Study highlights diabetes' substantial impact,
contributing to health disasters, such as amputations of limbs, blindness, and severe …

Approximately 500 million individuals worldwide live with diabetes, with nearly 80% residing
in low-and middle-income nations. Type 2 diabetes, afflicting nine out of ten people with the …