In clinical practice, signs of exaggerated tendon tap reflexes associated with muscle
hypertonia are generally thought to be responsible for spastic movement disorders. Most …

Management of symptoms in multiple sclerosis (MS) has received little attention compared
with disease-modifying treatments. However, the effect of these symptoms on quality of life …

Besides immunomodulation and immunosuppression, the specific treatment of symptoms is
an essential component of the overall management of multiple sclerosis (MS). Symptomatic …

The range of symptoms which occur in multiple sclerosis (MS) can have disabling functional
consequences for patients and lead to significant reductions in their quality of life. MS …

Study design: Comprehensive review and systematic analyses. Objectives: Assess
published psychometric evidence for spinal cord injury (SCI) spasticity outcome measures …

The development of immunomodulatory therapies for multiple sclerosis (MS) has had
significant impact in altering the natural history of the disease. Although these agents reduce …

Antispastic medications that are directed to reduce clinical signs of spasticity, such as
exaggerated reflexes and muscle tone, do not improve the movement disorder. Medication …

Objective We study the effectiveness and safety of intrathecal baclofen therapy for the
treatment of spasticity and gait improvement in patients suffering from hereditary spastic …

Pain is a common concern among persons with spinal cord injury. Incidence of pain
following SCI can range anywhere from 48 to 92%(Britell & Mariano 1991; Cohen et al …

Introduction: Pain is a prominent complication in spinal cord injury (SCI). It can either occur
as a direct or as an indirect consequence of SCI and it often heavily influences the quality of …