Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant
cancers exhibit complex molecular mechanisms to hit back therapy under pharmacological …

Intervertebral disc degeneration (IDD) is a common cause of joint-related chronic disability
in elderly individuals worldwide. It seriously impacts the quality of life and inflicts a …

Rationale Lung cancer is the most prevalent form of cancer and has a high mortality rate,
making it a global public health concern. The N6-methyladenosine (m6A) modification is a …

Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

Although m6A modifications are associated with tumor progression, and anti-tumor immune
responses, the role of m6A regulators in HPV-related carcinogenesis has not been well …

Ferroptosis, a form of regulated cell death, has emerged as a crucial process in diverse
pathophysiological states, encompassing cancer, neurodegenerative ailments, and …

Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA
methylation is one of the most common modifications and is widely observed in eukaryotes …

N6-methyladenosine (m6A) has been reported as an important mechanism of post-
transcriptional regulation. Programmed death ligand 1 (PD-L1) is a primary immune …

Abstract N6-methyladenosine (m6A) methylation, the most prevalent and abundant RNA
modification in eukaryotes, has recently become a hot research topic. Several studies have …

Background Immunotherapy has become the first-line treatment for advanced non-small-cell
lung cancer (NSCLC), but most patients still fail to benefit or have disease progression …