The CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcome Study) and colchicine
trials suggest an important role of inflammasomes and their major product IL-1β (interleukin …

APOA1 and APOB are the structural proteins of high-density lipoprotein and APOB-
containing lipoproteins, such as low-density lipoprotein and very low-density lipoprotein …

Serum apolipoprotein C3 (APOC3) predicts incident cardiovascular events in people with
type 1 diabetes, and silencing of APOC3 prevents both lesion initiation and advanced lesion …

Increased circulating levels of apolipoprotein C3 (APOC3) predict cardiovascular disease
(CVD) risk in humans, and APOC3 promotes atherosclerosis in mouse models. APOC3's …

The relationship between metabolic and inflammatory pathways play a pathogenic role in
various cardiometabolic disorders and is potentially also involved in the pathogenesis of …

High-density lipoproteins (HDL) are complex endogenous nanoparticles involved in
important functions such as reverse cholesterol transport and immunomodulatory activities …

Inhibition of apoC3 is effective across all the spectrum of hypertriglyceridemia, might have a
favorable effect on hepatic steatosis (NAFLD) and the effect of apoC3 inhibition on …

With a great deal of interest we read the comment related to our manuscript entitled
'Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome …

Diabetes increases the risk of both cardiovascular disease and kidney disease. Notably,
most of the excess cardiovascular risk in people with diabetes is in those with kidney …

Background Guillain-Barre syndrome (GBS) is an immune-mediated inflammatory
peripheral neuropathy. This study aimed to conduct a systematic analysis of the serum lipids …