Exerkines in health, resilience and disease

LS Chow, RE Gerszten, JM Taylor… - Nature Reviews …, 2022 - nature.com
The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Effect of physical activity/exercise on oxidative stress and inflammation in muscle and vascular aging

M El Assar, A Álvarez-Bustos, P Sosa, J Angulo… - International Journal of …, 2022 - mdpi.com
Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

[HTML][HTML] International exercise recommendations in older adults (ICFSR): expert consensus guidelines

M Izquierdo, RA Merchant, JE Morley, SD Anker… - The journal of nutrition …, 2021 - Springer
The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews

LJ Geneen, RA Moore, C Clarke… - Cochrane database …, 2017 - cochranelibrary.com
Background Chronic pain is defined as pain lasting beyond normal tissue healing time,
generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep …

Update on the effects of physical activity on insulin sensitivity in humans

SR Bird, JA Hawley - BMJ open sport & exercise medicine, 2017 - bmjopensem.bmj.com
Purpose and methods This review presents established knowledge on the effects of physical
activity (PA) on whole-body insulin sensitivity (SI) and summarises the findings of recent …

Precision nutrition: a review of personalized nutritional approaches for the prevention and management of metabolic syndrome

J de Toro-Martín, BJ Arsenault, JP Després, MC Vohl - Nutrients, 2017 - mdpi.com
The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

Precision exercise medicine: understanding exercise response variability

R Ross, BH Goodpaster, LG Koch… - British journal of sports …, 2019 - bjsm.bmj.com
There is evidence from human twin and family studies as well as mouse and rat selection
experiments that there are considerable interindividual differences in the response of …

Physical activity as a critical component of first-line treatment for elevated blood pressure or cholesterol: who, what, and how?: a scientific statement from the American …

B Barone Gibbs, MF Hivert, GJ Jerome, WE Kraus… - …, 2021 - Am Heart Assoc
Current guidelines published by the American Heart Association and the American College
of Cardiology broadly recommend lifestyle approaches to prevent and treat elevated blood …

[HTML][HTML] Exercise metabolism and the molecular regulation of skeletal muscle adaptation

B Egan, JR Zierath - Cell metabolism, 2013 - cell.com
Preservation of aerobic fitness and skeletal muscle strength through exercise training can
ameliorate metabolic dysfunction and prevent chronic disease. These benefits are mediated …

Exercise for hypertension: a prescription update integrating existing recommendations with emerging research

LS Pescatello, HV MacDonald, L Lamberti… - Current hypertension …, 2015 - Springer
Hypertension is the most common, costly, and preventable cardiovascular disease risk
factor. Numerous professional organizations and committees recommend exercise as initial …