Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
[HTML][HTML] The long road toward COVID-19 herd immunity: vaccine platform technologies and mass immunization strategies
LSF Frederiksen, Y Zhang, C Foged… - Frontiers in …, 2020 - frontiersin.org
There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides
AL Hilchie, K Wuerth, REW Hancock - Nature chemical biology, 2013 - nature.com
Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …
antimicrobial activities. They have since been found to exhibit multifaceted …
[HTML][HTML] Cathelicidins modulate TLR-activation and inflammation
MR Scheenstra, RM Van Harten… - Frontiers in …, 2020 - frontiersin.org
Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
Peptide design for antimicrobial and immunomodulatory applications
EF Haney, REW Hancock - Peptide Science, 2013 - Wiley Online Library
The increasing threat of antibiotic resistance in pathogenic bacteria and the dwindling
supply of antibiotics available to combat these infections poses a significant threat to human …
supply of antibiotics available to combat these infections poses a significant threat to human …
Controlled human infection models to accelerate vaccine development
RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
[HTML][HTML] Pertussis re-emergence in the post-vaccination era
E Chiappini, A Stival, L Galli, M De Martino - BMC infectious diseases, 2013 - Springer
Background Resurgence of pertussis in the post-vaccination era has been reported in
Western countries. A shift of cases from school-age children to adolescents, adults and …
Western countries. A shift of cases from school-age children to adolescents, adults and …
[HTML][HTML] Swine as biomedical animal model for T-cell research—Success and potential for transmittable and non-transmittable human diseases
T Käser - Molecular immunology, 2021 - Elsevier
Swine is biologically one of the most relevant large animal models for biomedical research.
With its use as food animal that can be exploited as a free cell and tissue source for research …
With its use as food animal that can be exploited as a free cell and tissue source for research …
What is wrong with pertussis vaccine immunity? The problem of waning effectiveness of pertussis vaccines
N Burdin, LK Handy, SA Plotkin - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …
The pertussis problem
SA Plotkin - Clinical infectious diseases, 2014 - academic.oup.com
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