Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …

Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …

Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …

The increasing threat of antibiotic resistance in pathogenic bacteria and the dwindling
supply of antibiotics available to combat these infections poses a significant threat to human …

The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Background Resurgence of pertussis in the post-vaccination era has been reported in
Western countries. A shift of cases from school-age children to adolescents, adults and …

Swine is biologically one of the most relevant large animal models for biomedical research.
With its use as food animal that can be exploited as a free cell and tissue source for research …

Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

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