MicroRNA epigenetic signatures in human disease
K Piletič, T Kunej - Archives of toxicology, 2016 - Springer
MicroRNAs (miRNAs) are short non-coding RNAs that act as important regulators of gene
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
MethHC: a database of DNA methylation and gene expression in human cancer
Abstract We present MethHC (http://MethHC. mbc. nctu. edu. tw), a database comprising a
systematic integration of a large collection of DNA methylation data and mRNA/microRNA …
systematic integration of a large collection of DNA methylation data and mRNA/microRNA …
Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment
P Li, JX Shan, XH Chen, D Zhang, LP Su, XY Huang… - Cell research, 2015 - nature.com
Tumor initiation and growth depend on its microenvironment in which cancer-associated
fibroblasts (CAFs) in tumor stroma play an important role. Prostaglandin E2 (PGE2) and …
fibroblasts (CAFs) in tumor stroma play an important role. Prostaglandin E2 (PGE2) and …
The emerging role of miRNA clusters in breast cancer progression
Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …
expression of the target genes. Large number of miRNAs are organized into defined units …
Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer
M Ma, C Li, Y Zhang, M Weng, M Zhang, Y Qin… - Molecular cancer, 2014 - Springer
Background Protein coding genes account for only about 2% of the human genome,
whereas the vast majority of transcripts are non-coding RNAs including long non-coding …
whereas the vast majority of transcripts are non-coding RNAs including long non-coding …
Aberrant miRNA promoter methylation and EMT‐involving miRNAs in breast cancer metastasis: diagnosis and therapeutic implications
Breast cancer (BC) is the most prevalent cancer in women worldwide. Although extensive
studies are ongoing concerning its intricate molecular mechanisms, development of novel …
studies are ongoing concerning its intricate molecular mechanisms, development of novel …
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer
H Jiménez-Wences, O Peralta-Zaragoza… - Oncology …, 2014 - spandidos-publications.com
Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect
gene expression. The progression from precursor lesions to invasive cervical cancer is …
gene expression. The progression from precursor lesions to invasive cervical cancer is …
DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression
IV Pronina, VI Loginov, AM Burdennyy, MV Fridman… - Gene, 2017 - Elsevier
The methylation of promoter CpG islands and the interaction between microRNAs (miRNAs)
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …
A systematic review of circulatory microRNAs in major depressive disorder: potential biomarkers for disease prognosis
Major depressive disorder (MDD) is a neuropsychiatric disorder, which remains challenging
to diagnose and manage due to its complex endophenotype. In this aspect, circulatory …
to diagnose and manage due to its complex endophenotype. In this aspect, circulatory …