[HTML][HTML] Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance
Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …
[HTML][HTML] Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?
The notion of exploiting the regenerative potential of the human brain in physiological aging
or neurological diseases represents a particularly attractive alternative to conventional …
or neurological diseases represents a particularly attractive alternative to conventional …
[HTML][HTML] Emerging roles of RNA-binding proteins in neurodevelopment
AS Parra, CA Johnston - Journal of Developmental Biology, 2022 - mdpi.com
Diverse cell types in the central nervous system (CNS) are generated by a relatively small
pool of neural stem cells during early development. Spatial and temporal regulation of stem …
pool of neural stem cells during early development. Spatial and temporal regulation of stem …
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus
C Gasperini, K Tuntevski, S Beatini, R Pelizzoli… - EMBO …, 2023 - embopress.org
Adult neural progenitor cells (aNPCs) ensure lifelong neurogenesis in the mammalian
hippocampus. Proper regulation of aNPC fate has thus important implications for brain …
hippocampus. Proper regulation of aNPC fate has thus important implications for brain …
[HTML][HTML] Combinational treatments of RNA interference and extracellular vesicles in the spinocerebellar ataxia
Y Ding, Y Zhang, X Liu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disease (ND)
with a high mortality rate. Symptomatic treatment is the only clinically adopted treatment …
with a high mortality rate. Symptomatic treatment is the only clinically adopted treatment …
Considering Context-Specific microRNAs in Ischemic Stroke with Three “W”: Where, When, and What
C Chang, Y Wang, R Wang, X Bao - Molecular Neurobiology, 2024 - Springer
MicroRNAs are short non-coding RNA molecules that function as critical regulators of
various biological processes through negative regulation of gene expression post …
various biological processes through negative regulation of gene expression post …
[HTML][HTML] PIWI-Interacting RNAs: A Pivotal Regulator in Neurological Development and Disease
X Pan, W Dai, Z Wang, S Li, T Sun, N Miao - Genes, 2024 - mdpi.com
PIWI-interacting RNAs (piRNAs), a class of small non-coding RNAs (sncRNAs) with 24–32
nucleotides (nt), were initially identified in the reproductive system. Unlike microRNAs …
nucleotides (nt), were initially identified in the reproductive system. Unlike microRNAs …
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental …
YF Liu, HT Liu, C Chang, CX Yang, XN Liu… - … Journal of Surgery, 2024 - journals.lww.com
Background: Ischemic stroke is a common neurovascular disorder with high morbidity and
mortality. However, the underlying mechanism of stereotactically intracerebral …
mortality. However, the underlying mechanism of stereotactically intracerebral …
Identification of Differentially Expressed MicroRNAs in the Rat Hippocampus during Adolescence through an Epigenome-Wide Analysis
A Vázquez de Ágredos Martín Gil, P Rovira Lorente… - 2024 - karger.com
Introduction: Epigenetic mechanisms involving microRNAs (miRNAs) play a fundamental
role in many biological processes, particularly during prenatal and early postnatal …
role in many biological processes, particularly during prenatal and early postnatal …
[PDF][PDF] Stem Cell Therapy in Treatment of Traumatic Brain Injury: A Systematic Review
G Farzanegan, HR Javadzade, M Anbarlouei - Trauma Monthly, 2023 - traumamon.com
Introduction: Cell therapy is broadly applied to the cure of the majority of diseases,
particularly Traumatic Brain Injury) TBI). The study aimed to review stem cell therapy in the …
particularly Traumatic Brain Injury) TBI). The study aimed to review stem cell therapy in the …