A serpin with a finger in many PAIs: PAI-1's central function in thromboinflammation and cardiovascular disease
GB Morrow, CS Whyte, NJ Mutch - Frontiers in cardiovascular …, 2021 - frontiersin.org
Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor
(serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue …
(serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue …
Past, present, and future perspectives of plasminogen activator inhibitor 1 (PAI-1)
GB Morrow, NJ Mutch - Seminars in thrombosis and …, 2023 - thieme-connect.com
Plasminogen activator inhibitor 1 (PAI-1), a SERPIN inhibitor, is primarily known for its
regulation of fibrinolysis. However, it is now known that this inhibitor functions and …
regulation of fibrinolysis. However, it is now known that this inhibitor functions and …
Increased systolic and diastolic blood pressure is associated with altered gut microbiota composition and butyrate production in early pregnancy
LF Gomez-Arango, HL Barrett, HD McIntyre… - …, 2016 - Am Heart Assoc
The risk of developing pregnancy-induced hypertension and preeclampsia is higher in
obese pregnant women. In obesity, the composition of the gut microbiota is altered. Obesity …
obese pregnant women. In obesity, the composition of the gut microbiota is altered. Obesity …
Relationship between plasma plasminogen activator inhibitor-1 and hypertension in American Indians: findings from the strong heart study
H Peng, F Yeh, G De Simone, LG Best… - Journal of …, 2017 - journals.lww.com
Objectives: Deficient plasminogen activator inhibitor-1 (PAI-1) prevented hypertension in
mice. Plasma PAI-1 was associated with hypertension in cross-sectional analyses, but the …
mice. Plasma PAI-1 was associated with hypertension in cross-sectional analyses, but the …
Exercise‐induced pulse wave velocity changes in untreated patients with essential hypertension: the effect of an angiotensin receptor antagonist
E Gkaliagkousi, E Gavriilaki… - The Journal of …, 2014 - Wiley Online Library
This study investigates arterial stiffness changes after acute exercise in young patients with
untreated, recently diagnosed grade I essential hypertension (UH) compared with …
untreated, recently diagnosed grade I essential hypertension (UH) compared with …
Effects of acute and chronic exercise in patients with essential hypertension: benefits and risks
E Gkaliagkousi, E Gavriilaki… - American journal of …, 2015 - academic.oup.com
The importance of regular physical activity in essential hypertension has been extensively
investigated over the last decades and has emerged as a major modifiable factor …
investigated over the last decades and has emerged as a major modifiable factor …
Tracking Biomarker Responses to Exercise in Hypertension
E Trillaud, P Klemmer, SK Malin… - Current Hypertension …, 2023 - Springer
Abstract Purpose of Review Strong evidence is evolving that physical exercise prevents
hypertension and reduces blood pressure in patients with pre-and manifest HTN. Yet …
hypertension and reduces blood pressure in patients with pre-and manifest HTN. Yet …
Acute exercise-induced changes in hemostatic and fibrinolytic properties: analogies, similarities, and differences between normotensive subjects and patients with …
A Braschi - Platelets, 2019 - Taylor & Francis
Following acute exercise, normotensive and hypertensive subjects both undergo changes in
hemostatic and fibrinolytic properties, but the hypertensive patient's response to exercise is …
hemostatic and fibrinolytic properties, but the hypertensive patient's response to exercise is …
Interplay between angiotensin II type 1 receptor and thrombin receptor revealed by bioluminescence resonance energy transfer assay
The key hormone of the renin-angiotensin system (RAS), angiotensin II (AngII), and thrombin
are known to play major roles in the vascular system and its related disorders. Previous …
are known to play major roles in the vascular system and its related disorders. Previous …
Acute exercise-induced inflammatory and thrombotic response in hypertensive patients
CI Liakos, C Aggeli, KP Toutouzas, MI Markou… - European Journal of …, 2024 - Springer
Purpose Vigorous physical activity may acutely trigger the onset of an acute coronary
syndrome especially in sedentary persons with established cardiovascular risk factors such …
syndrome especially in sedentary persons with established cardiovascular risk factors such …