Single-cell analysis has become an established method to study cell heterogeneity and for
rare cell characterization. Despite the high cost and technical constraints, applications are …

Technologies capable of cell separation based on cell images provide powerful tools
enabling cell selection criteria that rely on spatially or temporally varying properties. Image …

Heterogeneity in cell populations is a phenomenon encountered in virtually all biological
systems, in whole tissues and cell cultures and from bacterial to mammalian cells. Moreover …

Adoptive T cell therapies rely on the production of T cells with an antigen receptor that
directs their specificity toward tumor-specific antigens. Methods for identifying relevant T cell …

Older adults suffer a disproportionate burden of influenza-related morbidity and mortality
typically attributed to defects in the aging immune system collectively known as …

A common procedure performed throughout biomedical research is the selection and
isolation of biological entities such as organelles, cells and organoids from a mixed …

Enzymopathy disorders are the result of missing or defective enzymes. Among these
enzymopathies, mucopolysaccharidosis type I is a rare genetic lysosomal storage disorder …

Chimeric antigen receptor T (CAR‐T) cell immunotherapies have seen success in treating
hematological malignancies in recent years; however, the results can be highly variable …

Understanding biological heterogeneity at the single cell level is required for advancing
insights into the complexity of human physiology and diseases. While advances in …

Polydimethylsiloxane (PDMS) membranes can act as sensing elements, barriers, and
substrates, yet the low rigidity of the elastomeric membranes can limit their practical use in …