Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …

Recent studies have suggested that body composition is key to health and disease. First, fat
tissue is a complex, essential, and highly active metabolic and endocrine organ that …

Background: Stress is a state of homeostasis in the body being challenged, resulting in a
systemic response. It has become more prevalent in recent years and affects mental and …

Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in
longitudinal cohort epidemiological studies, and endocrinologic evidence suggests …

Background Devising novel prevention strategies for metabolic disorders will depend in part
on the careful elucidation of the common pathways for developing metabolic risks. The …

The hypothalamic paraventricular nucleus (PVN) controls neuroendocrine axes and the
autonomic nervous system to mount responses that cope with the energetic burdens of …

Metabolic syndrome (MetS) is a combination of factors which, collectively, increase
cardiovascular risk to a greater extent than each of them separately. Previous studies …

Recent reports on the effects of psychedelic-assisted therapies for mood disorders and
addiction, as well as the effects of psychedelics in the treatment of cluster headache, have …

Perivascular adipose tissue (PVAT) is no longer recognised as simply a structural support
for the vasculature, and we now know that PVAT releases vasoactive factors which modulate …