Immunoglobulin light chain amyloidosis: 2020 update on diagnosis, prognosis, and treatment

MA Gertz - American journal of hematology, 2020 - Wiley Online Library
Abstract Disease Overview Immunoglobulin light chain amyloidosis is a clonal,
nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy …

AL amyloidosis: advances in diagnostics and treatment

R Ryšavá - Nephrology Dialysis Transplantation, 2019 - academic.oup.com
AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic
disease characterized by an amyloid deposition process affecting many organs, and which …

A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis

G Palladini, U Hegenbart, P Milani… - Blood, The Journal …, 2014 - ashpublications.org
The kidney is involved in 70% of patients with immunoglobulin light-chain (AL) amyloidosis,
but little is known on progression or reversibility of renal involvement, and criteria for renal …

[HTML][HTML] Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: long-term results of a risk-adapted approach

G Palladini, P Milani, A Foli, L Obici, F Lavatelli… - …, 2014 - ncbi.nlm.nih.gov
The combination of oral melphalan and dexamethasone is considered standard therapy for
patients with light-chain amyloidosis ineligible for autologous stem cell transplantation …

Immunoglobulin light chain amyloidosis: 2016 update on diagnosis, prognosis, and treatment

MA Gertz - American journal of hematology, 2016 - Wiley Online Library
Disease Overview Immunoglobulin light chain amyloidosis is a clonal, nonproliferative
plasma cell disorder in which fragments of immunoglobulin light chain are deposited in …

Immunoglobulin light chain amyloidosis: 2018 Update on diagnosis, prognosis, and treatment

MA Gertz - American journal of hematology, 2018 - Wiley Online Library
Abstract Disease Overview Immunoglobulin light chain amyloidosis is a clonal,
nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy …

Depth of organ response in AL amyloidosis is associated with improved survival: grading the organ response criteria

E Muchtar, A Dispenzieri, N Leung, MQ Lacy, FK Buadi… - Leukemia, 2018 - nature.com
Organ recovery following anti-plasma cell therapy is associated with improved outcome in
patients with AL amyloidosis. Current organ response criteria do not consider the depth of …

Immunoglobulin light chain amyloidosis: 2014 update on diagnosis, prognosis, and treatment

MA Gertz - American journal of hematology, 2014 - Wiley Online Library
Disease Overview: Immunoglobulin light chain amyloidosis is a clonal, nonproliferative
plasma cell disorder in which fragments of immunoglobulin light chain are deposited in …

Renal amyloidosis: presentation, diagnosis, and management

R Gurung, T Li - The American Journal of Medicine, 2022 - Elsevier
More than 35 amyloid precursor proteins have been identified and many have tropism for
the kidney. Renal amyloidosis is most commonly seen in AL and AA amyloidosis and the …

Monoclonal gammopathy: The good, the bad and the ugly

SV Glavey, N Leung - Blood reviews, 2016 - Elsevier
Monoclonal gammopathy of undetermined significance (MGUS) is a condition characterized
by the presence of a monoclonal gammopathy (MG) in which the clonal mass has not …