Serum levels of liver enzymes, such as alanine transaminase, aspartate transaminase, and
α-fetoprotein, provide insight into liver function and are used during treatment of liver …

Nonalcoholic fatty liver disease (NAFLD) is a chronic, frequently progressive condition that
develops in response to excessive hepatocyte fat accumulation (ie, steatosis) in the absence …

Acetaminophen (APAP, paracetamol) poisoning is a leading cause of acute liver failure
(ALF) in humans and induces hepatocyte necrosis, followed by activation of the innate …

Hepatocytes are dynamic cells that, upon injury, can alternate between nondividing
differentiated and dedifferentiated proliferating states in vivo. However, in two‐dimensional …

Background & Aims A genome-wide association study (GWAS) of 280 cases identified the
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …

In the last decade, several studies have been focused on revealing the microRNA (miRNA)
repertoire and determining their functions in farm animals such as poultry, pigs, cattle, and …

Genetic factors strongly influence risk of common human diseases and treatment outcomes
but the causative variants remain largely unknown; this gap has been called the 'missing …

MicroRNAs (miRNAs) are critical regulators of gene expression, and their role in a wide
variety of biological processes, including host antimicrobial defense, is increasingly well …

UDP-glucuronosyltransferases (UGTs) are important phase II drug metabolism enzymes.
The aim of this study was to explore the relationship between age and changes in mRNA …

Competing endogenous RNAs (ceRNAs) are RNA molecules that sequester shared
microRNAs (miRNAs) thereby affecting the expression of other targets of the miRNAs …