Based on their mechanism of action, anti-tumor drugs that target the cell cycle can be
generally divided into three categories, namely, blocking DNA synthesis, causing DNA …

Over the past three decades, the Isolated Perfused Rat Kidney (IPK) has been used to study
numerous aspects of renal drug disposition. Among the available ex-vivo methods to study …

Gentamicin (GM) is an effective antibiotic against severe gram‐negative infections. However
it can produce nephrotoxicity in human. Reactive oxygen species (ROS) have been …

Alogliptin benzoate, a member of dipeptidyl peptidase‐4 inhibitors, is a recent drug
developed by Takeda Pharmaceutical Company for the treatment of Type 2 diabetes; it …

Leishmaniasis is a group of diseases caused by a protozoa parasite from one of over 20
Leishmania species. Depending on the tissues infected, these diseases are classified as …

To test the hypothesis that activation of the transient receptor potential vanilloid type 1
(TRPV1) channels leads to natriuresis and diuresis via an increase in glomerular filtration …

Objectives. Ischemic injury to the renal allograft prior to implantation is considered as the
major cause of primary non and never-function (PNF) and delayed graft function (DGF) …

Drug analysis is important in several phases of drug development, such as formulation,
stability studies and quality control. The importance of reliable analytical methods for drug …

Background: There have been many studies in recent years concerning the role of nitric
oxide (NO) in acute renal failure (ARF). In this study, the effects of the inhibition or the …

A sensitive capillary electrophoretic method with on‐line sample preconcentration by large
volume sample stacking has been developed for determination of the anti‐microbial agent …