Defensins are a well-characterised group of small, disulphide-rich, cationic peptides that are
produced by essentially all eukaryotes and are highly diverse in their sequences and …

The α-helix is the most commonly found natural secondary structure in proteins and is
intrinsic to many protein–protein interactions involved in important biological functions …

Disulfide bridge formation was investigated in helical aromatic oligoamide foldamers.
Depending on the position of thiol‐bearing side chains, exclusive intramolecular or …

The design, synthesis, and characterization of a folded high-affinity metal-binding peptide is
described. Based on the previously described folded peptide NTH-18, in which an α-helix …

Surface expression of α-(2, 8)-linked polymers of sialic acid in adult tissues has been
correlated with metastasis of several human cancers. One approach to chemotherapeutic …

ABSTRACT Preclinical Research Miniature proteins are a class of oligopeptide
characterized by their short sequence lengths and ability to adopt well‐folded, three …

Early onset epileptic encephalopathies that occur in very early childhood are rare but
particularly catastrophic forms of epilepsy that are invariably associated with significant …

Positively constrained: the first examples of photocontrolled RNA binding peptides are
described. The large number of positively charged sides chains in the Rev response …

The high photon flux at third-generation synchrotron sources can inflict significant primary
radiation damage upon macromolecular crystals, even when the crystals are cryocooled …

Foldamers are chain molecules (oligomer or polymers) that fold into a conformationally
ordered state when in solution. These polymers have been shown to have applications in …