Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
Self‐assembling peptide‐based hydrogels for wound tissue repair
T Guan, J Li, C Chen, Y Liu - Advanced Science, 2022 - Wiley Online Library
Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Multifunctional hydrogels for the healing of diabetic wounds
T Xiang, Q Guo, L Jia, T Yin, W Huang… - Advanced …, 2024 - Wiley Online Library
The healing of diabetic wounds is hindered by various factors, including bacterial infection,
macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen …
macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen …
Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
Highly stretchable and biocompatible wrinkled nanoclay‐composite hydrogel with enhanced sensing capability for precise detection of myocardial infarction
J Zhang, S Shen, R Lin, J Huang, C Pu… - Advanced …, 2023 - Wiley Online Library
It is challenging to balance high biocompability with good mechanical–electrical sensing
performance, especially when triggering inflammatory stress response after in vivo …
performance, especially when triggering inflammatory stress response after in vivo …
Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine
Z Zhang, C He, X Chen - Advanced Materials, 2024 - Wiley Online Library
The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …
Toward a better regeneration through implant‐mediated immunomodulation: harnessing the immune responses
Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …
physiological processes wherein immune responses play a crucial role to enable tissue …
Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy
X Cui, C Ma, V Vasudevaraja, J Serrano, J Tong… - Elife, 2020 - elifesciences.org
Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains
unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and …
unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and …
Rational design of hydrogels for immunomodulation
The immune system protects organisms against endogenous and exogenous harm and
plays a key role in tissue development, repair and regeneration. Traditional …
plays a key role in tissue development, repair and regeneration. Traditional …