The circadian clock in cancer development and therapy

L Fu, NM Kettner - Progress in molecular biology and translational …, 2013 - Elsevier
Most aspects of mammalian function display circadian rhythms driven by an endogenous
clock. The circadian clock is operated by genes and comprises a central clock in the brain …

Circadian dysfunction in disease

DA Bechtold, JE Gibbs, ASI Loudon - Trends in pharmacological sciences, 2010 - cell.com
The classic view of circadian timing in mammals emphasizes a light-responsive 'master
clock'within the hypothalamus which imparts temporal information to the organism. Recent …

Circadian nature of immune function

RW Logan, DK Sarkar - Molecular and cellular endocrinology, 2012 - Elsevier
The primary physiological role of the circadian system is to synchronize and coordinate
organ systems, particularly in response to dynamics in the environment. The immune system …

Neuroimmunology of the circadian clock

AN Coogan, CA Wyse - Brain research, 2008 - Elsevier
Circadian timekeeping is a ubiquitous feature of all eukaryotes which allows for the
imposition of a biologically appropriate temporal architecture on an animal's physiology …

Circadian clocks and inflammation: reciprocal regulation and shared mediators

N Cermakian, S Westfall, S Kiessling - Archivum immunologiae et …, 2014 - Springer
The immune system is deeply interconnected with the endogenous 24-h oscillators of the
circadian system. Indeed, the connection between these two physiological systems occurs at …

Circadian and circannual regulation in the horse: internal timing in an elite athlete

BA Murphy - Journal of equine veterinary science, 2019 - Elsevier
Biological rhythms evolved to provide temporal coordination across all tissues and organs
and allow synchronization of physiology with predictable environmental cycles. Most …

A circadian clock in murine bone marrow-derived mast cells modulates IgE-dependent activation in vitro

X Wang, SP Reece, MR Van Scott, JM Brown - Brain, behavior, and …, 2011 - Elsevier
Circadian rhythm is expressed in most organisms, and many functions and parameters in
the immune system are associated with time-of-day. However, it is largely unknown if local …

Long-lasting effects of sepsis on circadian rhythms in the mouse

EK O'Callaghan, ST Anderson, PN Moynagh… - 2012 - journals.plos.org
Daily patterns of activity and physiology are termed circadian rhythms and are driven
primarily by an endogenous biological timekeeping system, with the master clock located in …

Persistence of clock gene expression in peripheral blood in dogs maintained under different photoperiod schedules

C Giannetto, F Arfuso, M Rizzo, E Giudice… - Chronobiology …, 2024 - Taylor & Francis
Dogs are the common pets adopted by humans, and their circadian behavior and
physiology are influenced by human habits. In many families, there is a change of lifestyle …

Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: Effects of photoperiod, environment and weaning

CA Wyse, X Zhang, M McLaughlin, SM Biello… - Physiology & …, 2018 - Elsevier
Entrainment of circadian rhythms (CR) to the light dark cycle has been well described under
controlled, experimental conditions. However, studies in rodents have reported that rhythms …