[HTML][HTML] Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

L Tang, GT Xu, JF Zhang - Neural regeneration research, 2023 - journals.lww.com
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease,
is the leading cause of visual impairment in diabetic patients. Many clinical features …

Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

[HTML][HTML] Considerations for polymers used in ocular drug delivery

MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Ocular drug delivery: present innovations and future challenges

V Gote, S Sikder, J Sicotte, D Pal - Journal of Pharmacology and …, 2019 - ASPET
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …

Corticosteroids in ophthalmology: Drug delivery innovations, pharmacology, clinical applications, and future perspectives

SA Gaballa, UB Kompella, O Elgarhy… - Drug Delivery and …, 2021 - Springer
Corticosteroids remain the mainstay of the treatment for various ocular conditions affecting
the ocular surface, anterior and posterior segments of the eye due to their anti-inflammatory …

[HTML][HTML] Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies

M Mofidfar, B Abdi, S Ahadian, E Mostafavi… - International journal of …, 2021 - Elsevier
Research in the development of ophthalmic drug formulations and innovative technologies
over the past few decades has been directed at improving the penetration of medications …

[HTML][HTML] Advanced formulation approaches for ocular drug delivery: state-of-the-art and recent patents

EB Souto, J Dias-Ferreira, A López-Machado… - Pharmaceutics, 2019 - mdpi.com
The eye presents extensive perspectives and challenges for drug delivery, mainly because
of the extraordinary capacity, intrinsic to this path, for drugs to permeate into the main …

[HTML][HTML] Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

Diabetic retinopathy, a vascular and inflammatory disease: therapeutic implications

F Semeraro, F Morescalchi, A Cancarini, A Russo… - Diabetes & …, 2019 - Elsevier
Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and
the leading cause of visual impairment in the working-age population in the Western world …

[HTML][HTML] Soft contact lenses as drug delivery systems: a review

I Rykowska, I Nowak, R Nowak - Molecules, 2021 - mdpi.com
This review describes the role of contact lenses as an innovative drug delivery system in
treating eye diseases. Current ophthalmic drug delivery systems are inadequate, particularly …