Over the past 10 years, knowledge of the burden, economic costs, and consequences of
malaria in pregnancy has improved, and the prevalence of malaria caused by Plasmodium …

Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …

Malaria in pregnancy still constitutes a particular medical challenge in tropical and
subtropical regions. Of the five Plasmodium species that are pathogenic to humans, infection …

Background. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) mediates
the binding and accumulation of infected erythrocytes (IE) to blood vessels and tissues …

Background. Placental malaria is caused by Plasmodium falciparum–infected erythrocytes
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …

Malaria during pregnancy due to Plasmodium falciparum or P. vivax is a major public health
problem in endemic areas, with P. falciparum causing the greatest burden of disease …

Background Malaria remains a major public health threat and tools sensitive to detect
infections in low malaria transmission areas are needed to progress elimination efforts …

Background Pregnancy-associated malaria (PAM) constitutes one of the most severe forms
of malaria infection leading to fetal growth restriction and high risk of infant death. The …

The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the
infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the …

Introduction: Placental malaria (PM) is a major public health problem that constitutes a
significant health concern for the mother, and especially for the developing fetus and …