Arterial stiffness and cardiovascular risk in hypertension

P Boutouyrie, P Chowienczyk, JD Humphrey… - Circulation …, 2021 - Am Heart Assoc
Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …

Pulse wave velocity in atherosclerosis

HL Kim, SH Kim - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Early detection of subclinical atherosclerosis is important to reduce patients' cardiovascular
risk. However, current diagnostic strategy focusing on traditional risk factors or using risk …

Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association

RR Townsend, IB Wilkinson, EL Schiffrin, AP Avolio… - …, 2015 - Am Heart Assoc
Townsend et al Vascular Research on Arterial Stiffness 699 pressure, blood flow, and
arterial diameter change with each heartbeat. In addition to the passive mechanical …

[HTML][HTML] The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on …

C Vlachopoulos, P Xaplanteris, V Aboyans… - Atherosclerosis, 2015 - Elsevier
While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Mechanisms of vascular smooth muscle contraction and the basis for pharmacologic treatment of smooth muscle disorders

FV Brozovich, CJ Nicholson, CV Degen, YZ Gao… - Pharmacological …, 2016 - ASPET
The smooth muscle cell directly drives the contraction of the vascular wall and hence
regulates the size of the blood vessel lumen. We review here the current understanding of …

Interaction between hypertension and arterial stiffness: an expert reappraisal

ME Safar, R Asmar, A Benetos, J Blacher… - …, 2018 - Am Heart Assoc
Safar et al Hypertension and Arterial Stiffness 797 amplification, though it actually refers to a
pressure waveform distortion rather than an amplification, the latter erroneously implying an …

Arterial stiffness, atherosclerosis and cardiovascular risk: Pathophysiologic mechanisms and emerging clinical indications

C Palombo, M Kozakova - Vascular pharmacology, 2016 - Elsevier
Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

Arterial stiffness as a risk factor for clinical hypertension

ME Safar - Nature Reviews Cardiology, 2018 - nature.com
In patients with uncomplicated essential hypertension, cardiac output remains within normal
ranges and intravascular volume is normal or low, assuming the presence of a sufficient …

Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects

Y Ben-Shlomo, M Spears, C Boustred, M May… - Journal of the American …, 2014 - jacc.org
Objectives: The goal of this study was to determine whether aortic pulse wave velocity
(aPWV) improves prediction of cardiovascular disease (CVD) events beyond conventional …

Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis

C Vlachopoulos, K Aznaouridis, C Stefanadis - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to calculate robust quantitative estimates of the
predictive value of aortic pulse wave velocity (PWV) for future cardiovascular (CV) events …