[HTML][HTML] In silico prediction of potential inhibitors for the main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing

Y Kumar, H Singh, CN Patel - Journal of infection and public health, 2020 - Elsevier
Background The rapidly enlarging COVID-19 pandemic caused by the novel SARS-corona
virus-2 is a global public health emergency of an unprecedented level. Unfortunately no …

SARS‐CoV‐2 in the context of past coronaviruses epidemics: Consideration for prenatal care

V Lambelet, M Vouga, L Pomar, G Favre… - Prenatal …, 2020 - Wiley Online Library
Since December 2019, the novel SARS‐CoV‐2 outbreak has resulted in millions of cases
and more than 200 000 deaths worldwide. The clinical course among nonpregnant women …

Prevalence, characteristics and challenges of late HIV diagnosis in Germany: an expert narrative review

C Boesecke, S Schellberg, J Schneider, G Schuettfort… - Infection, 2023 - Springer
Purpose We aimed to review the landscape of late HIV diagnosis in Germany and discuss
persisting and emerging barriers to earlier diagnosis alongside potential solutions. Methods …

Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial

EC João, RL Morrison, DE Shapiro, N Chakhtoura… - The Lancet …, 2020 - thelancet.com
Background Although antiretroviral regimens containing integrase inhibitors rapidly
suppress HIV viral load in non-pregnant adults, few published data from randomised …

Effects of initiating raltegravir-based versus efavirenz-based antiretroviral regimens during pregnancy on weight changes and perinatal outcomes: NICHD P1081

CM Coutinho, MG Warshaw, G Duarte… - JAIDS Journal of …, 2022 - journals.lww.com
Background: Integrase inhibitors have been associated with excess gestational weight gain
that may lead to adverse pregnancy outcomes (APOs). This post hoc analysis of NICHD …

[HTML][HTML] Computational screening of phytocompounds from Moringa oleifera leaf as potential inhibitors of SARS-CoV-2 Mpro

D AN, J Jt - 2020 - europepmc.org
Background: Coronavirus Disease (COVID-19), caused by novel SARS CoV-2 is rapidly
spreading all over the World creating a global public health emergency at unprecedented …

Therapeutic drug monitoring of HIV antiretroviral drugs in pregnancy: a narrative review

B O'Kelly, R Murtagh, JS Lambert - Therapeutic Drug Monitoring, 2020 - journals.lww.com
To date, therapeutic drug monitoring (TDM) has played an important role in the management
of pregnant HIV patients on highly active antiretroviral therapy. Historically, in pregnant …

Modern antiretroviral regimens in pregnant women: virologic outcomes and durability

C Smith, L Silveira, M Crotteau, K Garth, J Canniff… - AIDS, 2024 - journals.lww.com
Objectives: Data are lacking on the virologic efficacy and durability of modern antiretroviral
treatment (ART) regimens during pregnancy. We compared virologic outcomes at delivery …

Efficacy of three antiretroviral regimens initiated during pregnancy: clinical experience in Rio de Janeiro

ML Benamor Teixeira, TL Fuller… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Few studies have compared the clinical efficacy and adverse events of combined
antiretroviral therapy (cART) regimens in pregnant women seeking obstetrical care. The …

[PDF][PDF] Safety and efficacy of oral lopinavir/ritonavir in pediatric patients with coronavirus disease: a nationwide comparative analysis.

JM Lu, AF Zhou, XB Zhang, H Xu… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: Because of the limited treatment options available, oral lopinavir/ritonavir
(LPR) was used for treating coronavirus disease (COVID-19) in pediatric patients. This study …