The oxidation of proteins by free radicals is thought to play a major role in many oxidative
processes within cells and is implicated in a number of human diseases as well as ageing …

As the number of industrial applications for proteins continues to expand, the exploitation of
protein engineering becomes critical. It is predicted that protein engineering can generate …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

We have employed γ-irradiation at cryogenic temperatures (77 K and also∼ 6 K) of the
ternary complexes of camphor, dioxygen, and ferro-cytochrome P450cam to inject the …

Proteins comprise a majority of the dry weight of a cell, rendering them a major target for
oxidative modification. Oxidation of proteins can result in significant alterations in protein …

Hemoproteins, hemoglobin and myoglobin, once released from cells can cause severe
oxidative damage as a consequence of heme redox cycling between ferric and ferryl states …

Recent research has shown that myoglobin and hemoglobin play important roles in the
pathology of certain disease states, such as renal dysfunction following rhabdomyolysis and …

Protein oxidation is increasingly recognised as an important modulator of biochemical
pathways controlling both physiological and pathological processes. While much attention …

The release of cytochrome c from mitochondria is a crucial step in apoptosis, resulting in the
activation of the caspase proteases. A further consequence of cytochrome c release is the …

Hydrogen peroxide (H 2 O 2) triggers a redox cycle between ferric and ferryl hemoglobin
(Hb) leading to the formation of a transient protein radical and a covalent hemeprotein cross …