Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …

Vascular endothelial growth factor (VEGF) is a potent growth factor playing diverse roles in
vasculogenesis and angiogenesis. In the brain, VEGF mediates angiogenesis, neural …

Neurotropic herpesviruses can establish lifelong infection in humans and contribute to
severe diseases including encephalitis and neurodegeneration. However, the mechanisms …

This study concerns the self-assembly of virus-like particles (VLPs) composed of an
icosahedral virus protein coat encapsulating a functionalized spherical nanoparticle core …

Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections
result in the temporary loss of smell and taste in about one third of confirmed cases. Methods …

Our ability to understand the function of the nervous system is dependent upon defining the
connections of its constituent neurons. Development of methods to define connections within …

Bone marrow is the primary place of hematopoiesis, where the development, survival and
release of multipotent stem cells, progenitors, precursors and mature cells are under …

Whole transcriptome studies have become essential for understanding the complexity of
genetic regulation. However, the conventionally applied short-read sequencing platforms …

Several neuroinvasive viruses can be used to study the mammalian nervous system. In
particular, infection by pseudorabies virus (PRV), an α-herpesvirus with broad host range …

The coat proteins of many viruses spontaneously form icosahedral capsids around nucleic
acids or other polymers. Elucidating the role of the packaged polymer in capsid formation …