Co-delivery of dexamethasone and captopril by α8 integrin antibodies modified liposome-PLGA nanoparticle hybrids for targeted anti-inflammatory/anti-fibrosis …

L Zhou, Z Ye, E Zhang, L Chen, Y Hou… - International Journal …, 2022 - Taylor & Francis
Purpose Mesangial cells-mediated glomerulonephritis refers to a category of
immunologically mediated glomerular injuries characterized by infiltration of circulating …

Captopril alleviates oxidative damage in diabetic retinopathy

X Gao, K Liu, C Hu, K Chen, Z Jiang - Life Sciences, 2022 - Elsevier
Aims To primarily explore the mechanism of captopril in oxidative stress and investigate the
link between captopril alleviated oxidative damage and diabetic retinopathy (DR). Main …

The angiotensin-converting enzyme inhibitor, captopril, suppressed hepatic stellate cell activation via NF-kappaB or wnt3α/β-catenin pathway

Z Gu, L Fang, P Ma - Bioengineered, 2021 - Taylor & Francis
Activation of hepatic stellate cells (HSC) is associated with hepatic fibrogenesis, which is
one of complications of diabetes mellitus. Captopril possesses potent anti-inflammation …