Flourishing antibacterial strategies for osteomyelitis therapy

X Wang, M Zhang, T Zhu, Q Wei, G Liu… - Advanced …, 2023 - Wiley Online Library
Osteomyelitis is a destructive disease of bone tissue caused by infection with pathogenic
microorganisms. Because of the complex and long‐term abnormal conditions, osteomyelitis …

[HTML][HTML] Management of fracture-related infection in low resource settings: how applicable are the current consensus guidelines?

EK Tissingh, L Marais, A Loro, D Bose… - EFORT open …, 2022 - eor.bioscientifica.com
The global burden of fracture-related infection (FRI) is likely to be found in countries with
limited healthcare resources and strategies are needed to ensure the best available practice …

[HTML][HTML] What factors affect outcome in the treatment of fracture-related infection?

M McNally, R Corrigan, J Sliepen, M Dudareva… - Antibiotics, 2022 - mdpi.com
This international, multi-center study investigated the effect of individual components of
surgery on the clinical outcomes of patients treated for fracture-related infection (FRI). All …

[HTML][HTML] Comparison of Ilizarov bifocal, acute shortening and relengthening with bone transport in the treatment of infected, segmental defects of the tibia

IK Sigmund, J Ferguson, GAM Govaert… - Journal of Clinical …, 2020 - mdpi.com
This prospective study compared bifocal acute shortening and relengthening (ASR) with
bone transport (BT) in a consecutive series of complex tibial infected non-unions and …

Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis

Y Jian, YAO Jiang-Ling, W Zi-Quan, Z De-Lu… - Chinese Journal of …, 2021 - mednexus.org
Post-traumatic osteomyelitis (PTO) is a worldwide problem in the field of orthopaedic trauma.
So far, there is no ideal treatment or consensus-based gold standard for its management …

[HTML][HTML] Use of negative pressure wound therapy in patients with fracture-related infection more than doubles the risk of recurrence

V Sweere, J Sliepen, S Haidari, M Depypere… - Injury, 2022 - Elsevier
Purpose Fracture-related infection (FRI) is one of the most serious complications in
orthopedic trauma surgery. Despite its widespread use, the role of Negative Pressure …

[HTML][HTML] Soft-tissue reconstruction in lower-leg fracture-related infections: an orthoplastic outcome and risk factor analysis

SLC Müller, M Morgenstern, R Kuehl, T Muri… - Injury, 2021 - Elsevier
Introduction: Fracture-related infection (FRI) is a severe post-traumatic complication which is
occasionally accompanied by a deficient or even avital soft-tissue envelope. In these cases …

Treatment and outcome of fracture-related infection of the clavicle

J Sliepen, H Hoekstra, J Onsea, L Bessems… - Injury, 2023 - Elsevier
Introduction The number of operatively treated clavicle fractures has increased over the past
decades. Consequently, this has led to an increase in secondary procedures required to …

[HTML][HTML] Key aspects of soft tissue management in fracture-related infection: recommendations from an international expert group

LC Marais, S Hungerer, H Eckardt, C Zalavras… - Archives of Orthopaedic …, 2024 - Springer
A judicious, well-planned bone and soft tissue debridement remains one of the cornerstones
of state-of-the-art treatment of fracture-related infection (FRI). Meticulous surgical excision of …

[HTML][HTML] The surgical management of fracture-related infection. Surgical strategy selection and the need for early surgical intervention

LC Marais, CG Zalavras, FT Moriarty, R Kühl… - Journal of …, 2023 - Elsevier
The aim of this narrative review is to describe the various surgical management strategies
employed in fracture-related infection (FRI), to explore how they are selected and discuss …