The prevalence and cost of chronic pain is a major physical and mental health care problem
in the United States today. As a result, there has been a recent explosion of research on …

Mitochondria play a central role in the survival and death of neurons. The detailed
bioenergetic mechanisms by which isolated mitochondria generate ATP, sequester Ca2+ …

Many mammalian peripheral tissues have circadian clocks,,,; endogenous oscillators that
generate transcriptional rhythms thought to be important for the daily timing of physiological …

α-Synuclein (αSyn) aggregation and mitochondrial dysfunction both contribute to the
pathogenesis of Parkinson disease (PD). Although recent studies have suggested that …

Introduction• Classifying TBI‐Clinical injury severity‐Focal injury or diffuse injury• Clinical
characteristics‐Coma, confusion and subacute impairments‐Imaging TBI‐Focal and diffuse …

Cerebral postischemic reperfusion injury is defined as deterioration of ischemic brain tissue
that parallels and antagonizes the benefits of restoring cerebral circulation after therapeutic …

Minocycline mediates neuroprotection in experimental models of neurodegeneration. It
inhibits the activity,,,,, of caspase-1, caspase-3, inducible form of nitric oxide synthetase …

Death of oligodendrocyte (OL) precursors can be triggered in vitro by cystine deprivation, a
form of oxidative stress that involves depletion of intracellular glutathione. We report here …

Neuroradiologists may encounter, on a daily basis, a challenging diversity of neurologic
disorders, including stroke, trauma, epilepsy, and even neurodegenerative conditions, such …

Mitochondrial Ca2+ uptake through the recently discovered Mitochondrial Calcium Uniporter
(MCU) is controlled by its gatekeeper Mitochondrial Calcium Uptake 1 (MICU1). However …