Evolving concepts in the pathogenesis of uraemic cardiomyopathy
X Wang, JI Shapiro - Nature Reviews Nephrology, 2019 - nature.com
The term uraemic cardiomyopathy refers to the cardiac abnormalities that are seen in
patients with chronic kidney disease (CKD). Historically, this term was used to describe a …
patients with chronic kidney disease (CKD). Historically, this term was used to describe a …
Protein interaction and Na/K-ATPase-mediated signal transduction
X Cui, Z Xie - Molecules, 2017 - mdpi.com
The Na/K-ATPase (NKA), or Na pump, is a member of the P-type ATPase superfamily. In
addition to pumping ions across cell membrane, it is engaged in assembly of multiple …
addition to pumping ions across cell membrane, it is engaged in assembly of multiple …
Towards a comprehensive theory of obesity and a healthy diet: The causal role of oxidative stress in food addiction and obesity
TO Tobore - Behavioural brain research, 2020 - Elsevier
Background Obesity is a major public health problem whose prevalence has been rapidly
increasing in the United States (US), and globally. It is one of the leading causes of …
increasing in the United States (US), and globally. It is one of the leading causes of …
Na+/K+-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation
J Bejček, V Spiwok, E Kmoníčková, S Rimpelová - Molecules, 2021 - mdpi.com
Maintenance of Na+ and K+ gradients across the cell plasma membrane is an essential
process for mammalian cell survival. An enzyme responsible for this process, sodium …
process for mammalian cell survival. An enzyme responsible for this process, sodium …
Therapeutic efficacy of antioxidants in ameliorating obesity phenotype and associated comorbidities
S Tun, CJ Spainhower, CL Cottrill… - Frontiers in …, 2020 - frontiersin.org
Obesity has been a worldwide epidemic for decades. Despite the abundant increase in
knowledge regarding the etiology and pathogenesis of obesity, the prevalence continues to …
knowledge regarding the etiology and pathogenesis of obesity, the prevalence continues to …
The role of Na/K-ATPase signaling in oxidative stress related to obesity and cardiovascular disease
K Srikanthan, JI Shapiro, K Sodhi - Molecules, 2016 - mdpi.com
Na/K-ATPase has been extensively studied for its ion pumping function, but, in the past
several decades, has been identified as a scaffolding and signaling protein. Initially it was …
several decades, has been identified as a scaffolding and signaling protein. Initially it was …
The Na/K-ATPase signaling: from specific ligands to general reactive oxygen species
RD Pratt, CR Brickman, CL Cottrill, JI Shapiro… - International journal of …, 2018 - mdpi.com
The signaling function of the Na/K-ATPase has been established for 20 years and is widely
accepted in the field, with many excellent reports and reviews not cited here. Even though …
accepted in the field, with many excellent reports and reviews not cited here. Even though …
Attenuation of Na/K-ATPase mediated oxidant amplification with pNaKtide ameliorates experimental uremic cardiomyopathy
We have previously reported that the sodium potassium adenosine triphosphatase (Na/K-
ATPase) can effect the amplification of reactive oxygen species. In this study, we examined …
ATPase) can effect the amplification of reactive oxygen species. In this study, we examined …
[HTML][HTML] The physiological and clinical importance of sodium potassium ATPase in cardiovascular diseases
Y Yan, JI Shapiro - Current opinion in pharmacology, 2016 - Elsevier
Highlights•The sodium potassium adenosine triphosphatase (Na/K-ATPase) functions as a
scaffolding and signaling protein.•Both cardiotonic steroids and reactive oxygen species …
scaffolding and signaling protein.•Both cardiotonic steroids and reactive oxygen species …
Energy metabolism response induced by microplastic for marine dinoflagellate Karenia mikimotoi
T Zhao, L Tan, X Han, X Ma, K Lin, J Wang - Science of The Total …, 2023 - Elsevier
Microplastic contaminations threaten the entire marine ecosystem and cause severe
ecological stress. This study explored the energy metabolism change of Karenia mikimotoi …
ecological stress. This study explored the energy metabolism change of Karenia mikimotoi …