GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
JJ Meier - Nature Reviews Endocrinology, 2012 - nature.com
In healthy humans, the incretin glucagon-like peptide 1 (GLP-1) is secreted after eating and
lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon …
lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon …
Effects of GLP-1 on appetite and weight
M Shah, A Vella - Reviews in Endocrine and Metabolic Disorders, 2014 - Springer
Abstract Glucagon-like peptide 1 (GLP-1) is a cleavage product of the pre-proglucagon gene
which is expressed in the α-cells of the pancreas, the L-cells of the intestine, and neurons …
which is expressed in the α-cells of the pancreas, the L-cells of the intestine, and neurons …
The brain, appetite, and obesity
HR Berthoud, C Morrison - Annu. Rev. Psychol., 2008 - annualreviews.org
Food intake and energy expenditure are controlled by complex, redundant, and distributed
neural systems that reflect the fundamental biological importance of adequate nutrient …
neural systems that reflect the fundamental biological importance of adequate nutrient …
Obesity: pathophysiology and intervention
Obesity presents a major health hazard of the 21st century. It promotes co-morbid diseases
such as heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and …
such as heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and …
Peptides and food intake
C Sobrino Crespo, A Perianes Cachero… - Frontiers in …, 2014 - frontiersin.org
The mechanisms for controlling food intake involve mainly an interplay between gut, brain,
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …
The role of gut hormones and the hypothalamus in appetite regulation
K Suzuki, KA Simpson, JS Minnion, JC Shillito… - Endocrine …, 2010 - jstage.jst.go.jp
The World Health Organisation has estimated that by 2015 approximately 2.3 billion adults
will be overweight and more than 700 million obese. Obesity is associated with an increased …
will be overweight and more than 700 million obese. Obesity is associated with an increased …
Acute exercise and hormones related to appetite regulation: a meta-analysis
Background Understanding of the impact of an acute bout of exercise on hormones involved
in appetite regulation may provide insight into some of the mechanisms that regulate energy …
in appetite regulation may provide insight into some of the mechanisms that regulate energy …
Obesity and appetite control
K Suzuki, CN Jayasena… - Journal of Diabetes …, 2012 - Wiley Online Library
Obesity is one of the major challenges to human health worldwide; however, there are
currently no effective pharmacological interventions for obesity. Recent studies have …
currently no effective pharmacological interventions for obesity. Recent studies have …
Role of neuropeptides in appetite regulation and obesity–a review
S Arora - Neuropeptides, 2006 - Elsevier
Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …