Chromosomal instability (CIN) is a hallmark of human cancer, and it is associated with poor
prognosis, metastasis, and therapeutic resistance. CIN results from errors in chromosome …

Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

Organic photothermal nanoagents are promising candidates for treating primary tumors and
inhibiting metastasis. However, they often exhibit poor photostability, low absorptivity, or …

Triggering apoptosis remains an efficient strategy to treat cancer. However, apoptosis is no
longer a final destination since cancer cells can undergo partial apoptosis without dying …

Wound healing assay performed with automated microscopy is widely used in drug testing,
cancer cell analysis, and similar approaches. It is easy to perform, and the results are …

Background After chemotherapy, many cancer survivors suffer from long-lasting cognitive
impairment, colloquially known as “chemobrain.” However, the trajectories of cognitive …

Chemotherapy, the most widely accepted treatment for malignant tumors, is dependent on
cell death induced by various drugs including antimetabolites, alkylating agents, mitotic …

Inflammation triggered by infection or cellular necrosis is initiated by a battery of pattern-
recognition receptors, such as Toll-like receptors or IL-1 family receptors. Diverse forms of …

Cytotoxic therapy for breast cancer inhibits the growth of primary tumors, but promotes
metastasis to the sentinel lymph nodes through the lymphatic system. However, the effect of …

Cancer therapy reduces tumor burden via tumor cell death (“debris”), which can accelerate
tumor progression via the failure of inflammation resolution. Thus, there is an urgent need to …