Tissue‐scale biomechanical testing of brain tissue for the calibration of nonlinear material models

J Faber, J Hinrichsen, A Greiner, N Reiter… - Current …, 2022 - Wiley Online Library
Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …

Modeling traumatic brain injury in human cerebral organoids

S Ramirez, A Mukherjee, S Sepulveda… - Cells, 2021 - mdpi.com
Traumatic brain injury (TBI) is a head injury that disrupts the normal brain structure and
function. TBI has been extensively studied using various in vitro and in vivo models. Most of …

[HTML][HTML] Correlating the microstructural architecture and macrostructural behaviour of the brain

M Hoppstädter, D Püllmann, R Seydewitz, E Kuhl… - Acta Biomaterialia, 2022 - Elsevier
The computational simulation of pathological conditions and surgical procedures, for
example the removal of cancerous tissue, can contribute crucially to the future of medicine …

Alginate-based hydrogels show the same complex mechanical behavior as brain tissue

T Distler, E Schaller, P Steinmann… - Journal of the …, 2020 - Elsevier
Mimicking the mechanical properties of native human tissues is one key route in tissue
engineering. However, the successful creation of functional tissue equivalents requires the …

Experimental and computational approach to human brain modelling–aHEAD

M Ptak, M Dymek, M Sawicki, FAO Fernandes… - Archives of Civil and …, 2023 - Springer
The human head is a highly complex structure, with a combination of hard and soft tissues
and a variety of materials and interactions. Many researchers have used computational …

Dermal tissue penetration of in-plane silicon microneedles evaluated in skin-simulating hydrogel, rat skin and porcine skin

SI Bisgaard, LQ Nguyen, KL Bøgh, SS Keller - Biomaterials Advances, 2023 - Elsevier
Recently, microneedle-based sensors have been introduced as novel strategy for in situ
monitoring of biomarkers in the skin. Here, in-plane silicon microneedles with different …

Prediction of subdural haematoma based on a detailed numerical model of the cerebral bridging veins

JMC Costa, FAO Fernandes, RJA de Sousa - Journal of the Mechanical …, 2020 - Elsevier
Traumatic brain injury is one of the major causes of death and disability in the world. One of
the most frequent and deadly injury resulted from a head trauma is acute subdural …

Rate-and Region-Dependent Mechanical Properties of Göttingen Minipig Brain Tissue in Simple Shear and Unconfined Compression

GM Boiczyk, N Pearson, VB Kote… - Journal of …, 2023 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI), particularly from explosive blasts, is a major cause of casualties
in modern military conflicts. Computational models are an important tool in understanding …

[HTML][HTML] Machine learning reveals correlations between brain age and mechanics

M Hoppstädter, K Linka, E Kuhl, M Schmicke, M Böl - Acta biomaterialia, 2024 - Elsevier
Our brain undergoes significant micro-and macroscopic changes throughout its life cycle. It
is therefore crucial to understand the effect of aging on the mechanical properties of the …

Ballistic gelatine—what we see and what we get

CWA Schyma - International journal of legal medicine, 2020 - Springer
Since decades, 10% gelatine is used to visualize and estimate the energy transfer of
projectiles. The study performed investigates the correlation of the temporary cavity (TC) …