Background: Truncating variants in the TTN gene (TTNtv) are the commonest cause of
heritable dilated cardiomyopathy. This study aimed to study the phenotypes and outcomes …

Recent advances in RNA sequencing and bioinformatic analysis have allowed the
development of a new research field: circular RNAs (circRNAs). These members of the non …

Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular
dilation and systolic dysfunction in the absence of abnormal loading conditions or coronary …

The dog provides a large animal model of familial dilated cardiomyopathy for the study of
important aspects of this common familial cardiovascular disease. We have previously …

We have recently described a new peptide of the renin-angiotensin system, alamandine, a
derivative of angiotensin-(1–7). Mas-related G protein-coupled receptor member D (MrgD) …

Abstract Lamin A/C gene (LMNA)-related familial dilated cardiomyopathy (fDCM) is an
aggressive heart disease that often leads to transplantation and sudden death. The aim of …

A great many circular RNAs (circRNAs) exist in different types of mammalian cells. Previous
studies have verified that a low level of hsa_circ_0002320 is present in gastric cancer and …

As two members of the basic helix-loop-helix family of transcription factors, HAND1 and
HAND2 are both required for the embryonic cardiogenesis and postnatal ventricular …

A new familial dilated cardiomyopathy (FDCM) was found related to mutations in BAG3
gene. MicroRNAs (miRNAs) represent new targets of FDCM, although no studies have …

A splice site mutation in the canine pyruvate dehydrogenase kinase 4 (PDK4) gene has
been shown to be associated with the development of dilated cardiomyopathy (DCM) in …