Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases
P Chaudhary, P Janmeda, AO Docea… - Frontiers in …, 2023 - frontiersin.org
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …
body and occur as a side effect of many reactions that take place in the human body. Under …
Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
[HTML][HTML] Oxidative stress–Complex pathological issues concerning the hallmark of cardiovascular and metabolic disorders
Oxidative stress is a complex biological process characterized by the excessive production
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …
[HTML][HTML] Targeting p53 for the treatment of cancer
MJ Duffy, NC Synnott, S O'Grady, J Crown - Seminars in cancer biology, 2022 - Elsevier
Dysfunction of the TP53 (p53) gene occurs in most if not all human malignancies. Two
principal mechanisms are responsible for this dysfunction; mutation and downregulation of …
principal mechanisms are responsible for this dysfunction; mutation and downregulation of …
Copper in tumors and the use of copper-based compounds in cancer treatment
DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
Kaempferol: A key emphasis to its anticancer potential
A marked decrease in human cancers, including breast cancer, bone cancer, and cervical
cancer, has been linked to the consumption of vegetable and fruit, and the corresponding …
cancer, has been linked to the consumption of vegetable and fruit, and the corresponding …
A brief overview on antioxidant activity determination of silver nanoparticles
Z Bedlovičová, I Strapáč, M Baláž, A Salayová - Molecules, 2020 - mdpi.com
Our objective in this review article is to find out relevant information about methods of
determination of antioxidant activity of silver nanoparticles. There are many studies dealing …
determination of antioxidant activity of silver nanoparticles. There are many studies dealing …
[HTML][HTML] Molecular pathways associated with oxidative stress in diabetes mellitus
OM Ighodaro - Biomedicine & pharmacotherapy, 2018 - Elsevier
The role of oxidative stress in the occurrence and development of diabetes mellitus is both
critical and pivotal. Several molecular event cascade in different metabolic pathways such …
critical and pivotal. Several molecular event cascade in different metabolic pathways such …
Oxidative stress and cancer
JE Klaunig - Current pharmaceutical design, 2018 - ingentaconnect.com
Background: Cancer is considered a major cause of death worldwide. The etiology of cancer
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
The role of resveratrol in cancer therapy
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …
community for their potent effects against inflammation-driven diseases, including cancer. A …