Recent trends in biosensing research have motivated scientists and research professionals
to investigate the development of miniaturized bioanalytical devices to make them portable …

Abstract Heart-on-a-chip (HoC) has emerged as a highly efficient, cost-effective device for
the development of engineered cardiac tissue, facilitating high-throughput testing in drug …

Heart diseases have become the main killer threatening human health, and various
methods have been developed to study heart disease. Among them, heart-on-a-chip has …

Nanoplastics are global pollutants that have been increasingly released into the
environment following the degradation process of industrial and consumer products. These …

Drug-induced cardiotoxicity is a potentially severe side effect that can alter the contractility
and electrophysiology of the cardiomyocytes. Cardiotoxicity is generally assessed through …

Drug-induced cardiotoxicity is the primary cause of heart failure and leading to withdrawal of
drugs from the market. Although in vitro animal models are successfully used in fundamental …

Cardiovascular disease is currently a leading killer to human, while drug‐induced
cardiotoxicity remains the main cause of the withdrawal and attrition of drugs. Taking clinical …

The development of efficient tools for predicting drug-induced cardiotoxicity in the preclinical
phase would greatly benefit the drug development process. This study presents an SU-8 …

Mechanical stimulation within diaphragm-based cell culture platforms presents a promising
strategy to enhance cardiomyocyte maturation. However, most of the proposed techniques …

Cell culture substrates designed for myocardial applications are pivotal in promoting the
maturation and functional integration of cardiomyocytes. However, traditional in vitro models …