Bone degeneration associated with various diseases is increasing due to rapid aging,
sedentary lifestyles, and unhealthy diets. Living bone tissue has bioelectric properties critical …

Approximately 40% of treatments of chronic and recurrent osteomyelitis fail in part due to
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …

The skin serves as the interface between the human body and the environment and interacts
with the microbial community. The skin microbiota consists of microorganisms, such as …

The barrier function of host cells enables intracellular bacteria to evade the lethality of the
host immune system and antibiotics, thereby causing chronic and recurrent infections that …

Background Present work was aimed to gather accessible evidence on the eradication rates
and related postoperative complications of antibiotic-loaded calcium sulfate (CS) as an …

Formation of Staphylococcus aureus biofilm causes significant infections in the human body.
Biofilm forms through the aggregation of bacterial species and brings about many …

Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to
its intricate etiology and limited treatment options. Despite strides in surgical and …

As treatment of Staphylococcus aureus (S. aureus) osteomyelitis is often hindered by the
development of antibiotic tolerance, novel antibacterial therapeutics are required. Here we …

Tissue infection typically results from blood transmission or the direct inoculation of bacteria
following trauma. The pathogen-induced destruction of tissue prevents antibiotics from …

Implants and materials are indispensable in trauma and orthopedic surgery. The continuous
improvements of implant design have resulted in an optimized mechanical function that …