Long COVID-19 syndrome: a comprehensive review of its effect on various organ systems and recommendation on rehabilitation plans

Z Yan, M Yang, CL Lai - Biomedicines, 2021 - mdpi.com
The majority of people infected with SARS-CoV-2 fully recovered within a few weeks.
However, a considerable number of patients of different ages still suffer from long-lasting …

Venous thromboembolism in COVID-19: A systematic review and meta-analysis

A Kollias, KG Kyriakoulis, S Lagou… - Vascular …, 2021 - journals.sagepub.com
Severe coronavirus disease 2019 (COVID-19) is associated with increased risk of venous
thromboembolism events (VTE). This study performed a systematic review in …

Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre …

E Ramacciotti, LB Agati, D Calderaro, VCR Aguiar… - The Lancet, 2022 - thelancet.com
Background Patients hospitalised with COVID-19 are at risk for thrombotic events after
discharge; the role of extended thromboprophylaxis in this population is unknown. Methods …

Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

E Pretorius, M Vlok, C Venter, JA Bezuidenhout… - Cardiovascular …, 2021 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced
infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute …

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also …

A Kruger, M Vlok, S Turner, C Venter… - Cardiovascular …, 2022 - Springer
Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

Postdischarge thromboembolic outcomes and mortality of hospitalized patients with COVID-19: the CORE-19 registry

D Giannis, SL Allen, J Tsang, S Flint… - Blood, The Journal …, 2021 - ashpublications.org
Thromboembolic events, including venous thromboembolism (VTE) and arterial
thromboembolism (ATE), and mortality from subclinical thrombotic events occur frequently in …

Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Persistent endothelial dysfunction in post-acute COVID-19 syndrome: a case-control study

P Ambrosino, I Calcaterra, A Molino, P Moretta… - Biomedicines, 2021 - mdpi.com
Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus
disease 2019 (COVID-19) and its disabling complications. We designed a case-control …

Association of neutrophil activation, more than platelet activation, with thrombotic complications in coronavirus disease 2019

E Petito, E Falcinelli, U Paliani, E Cesari… - The Journal of …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 infection is associated with
hypercoagulability, which predisposes to venous thromboembolism (VTE). We analyzed …

Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
Introduction A hypercoagulable condition was described in patients with coronavirus
disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing …